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Zhengchaihuyin dripping pill

A technology of drinking dripping pills and Bupleurum bupleurum, applied in pill delivery, antibacterial drugs, antipyretics, etc., can solve the problems of hepatic and intestinal first-pass bioavailability, unfavorable medicines for patients, and physical hazards for staff, etc., to achieve effective Conducive to labor protection and environmental protection, avoiding the first-pass effect, and low labor intensity

Inactive Publication Date: 2005-05-18
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the preparation technology and other reasons, the oral preparations of most drugs have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the efficacy of the drug. It also directly affects the therapeutic effect, especially for traditional Chinese medicine preparations.
[0005] In addition, conventional oral dosage forms, due to the dry powder mixing, granulation and other processes in the preparation process, will produce relatively large dust pollution, which will cause harm to the health of the staff to a certain extent, and will also cause certain pollution to the environment.
At the same time, the production process of conventional oral preparations is complicated, and the production cost is high, which is not conducive to the medical treatment of patients with poor economic conditions. Therefore, it is necessary to seek better oral preparations of Zhengchaihuyin to meet the needs of clinical treatment and family use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0035] Now with the test of three groups of specific examples and the results thereof, the preparation method of Zhengchaihuyin dripping pills involved in the present invention will be further described.

[0036] [formula]

[0037] 1. Obtain an extract or dry powder containing active pharmaceutical ingredients according to the formula and process given in [Formula and Extraction of Raw Materials of Traditional Chinese Medicine];

[0038] 2. Substrate: polyethylene glycol 2000、4000、6000、8000、10000、2000 , stearic acid, sodium stearate, polyoxyl 40 stearate, glycerin gelatin, shellac, polyoxyethylene monostearate, polyether, sodium carboxymethyl starch, sodium lauryl sulfate, etc. pharmaceutically acceptable carrier;

[0039] 3. Proportioning (in g or kg, in parts by weight): extract (dry powder): matrix = 1: (1-9);

[0040] [test results]

[0041] Experiment 1: In order to observe the difference in quality of the Zhengchaihuyin dripping pills prepared when the extract or dry...

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PUM

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Abstract

The present invention discloses a kind of orally taken medicine preparation for treating disease caused by exogenous wind and cold, fever, aversion to cold, headache, etc., and is especially Zhengchaihuyin dripping pill with the extract of traditional Zhengchaihuyin recipe and possessing antiviral and antibacterial effect. The Zhengchaihuyin dripping pill of the present invention has high bioavailability, fast medicine release, quick acting, less toxic side effect, pollution-free production process and low cost. The Zhengchaihuyin dripping pill of the present invention is prepared based on traditional recipe.

Description

technical field [0001] The invention relates to an oral preparation of a therapeutic drug mainly used for exogenous wind-cold, fever and chills, headache, body pain, etc., in particular to the active ingredient of Zhengchaihuyin traditional Chinese medicine, which has antiviral and antibacterial properties. Oral drop pill formulations. Background technique [0002] "Zhengchaihu Drink" is the representative prescription of Jiebiao Pingsan in "Jingyue Quanshu" by Zhang Jingyue, a famous doctor in Ming Dynasty. It is composed of Bupleurum, tangerine peel, Fangfeng, red peony, ginger, and licorice. , Indications for the early onset of exogenous wind-cold, aversion to cold and fever, no sweat, headache, nasal congestion, sneezing, itchy throat and cough, sore limbs and other symptoms. "Jingyue Quanshu" contains six prescriptions named "Chaihuyin", the first five are called "Chaihuyin 1, Chaihuyin 2, ..., Chaihuyin 5". The sixth one is based on the previous five prescriptions, w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P29/00A61P31/04A61P31/12
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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