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Medicine composition for treating eye disease, and its use

An eye disease and composition technology, which is applied in the field of pharmaceutical compositions for the treatment of eye diseases, can solve the problems of complex use of traditional Chinese medicine, influence the difference in drug efficacy and drug efficacy, etc. Painful effects of patients

Inactive Publication Date: 2006-11-29
CHENGDU DIKANG PHARMA INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the complexity of the use of traditional Chinese medicine, the choice and dosage of medicines are different, which directly affect the efficacy of the medicine and the difference in efficacy. At present, there are no reports on the usage and dosage of the raw materials of ginseng and Radix Ophiopogon japonicus and their effective ratios, and the treatment of eye diseases.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1 Extraction of pharmaceutical bulk drug of the present invention

[0026] 1. Pretreatment of medicinal materials

[0027] The qualified ginseng (red ginseng) and Ophiopogon japonicus medicinal materials are selected, washed, dried and crushed into flakes or granules respectively.

[0028] 2. Extraction

[0029] 1. Extraction of ginseng

[0030] Weigh red and add 15-30 times of water, boil at 80-90°C for 3 hours, filter; add 15-30 times of water to boil, keep at 85-95°C for 2 hours, filter; add 15 -30 times of water is boiled and then kept at 85-95° C. for 1.5 hours, filtered, combined filtrates, and centrifuged to remove sediment to obtain ginseng water extract.

[0031] 2. Ophiopogon japonicus extract

[0032] Weigh a certain amount of Ophiopogon japonicus, add 15-30 times of water to boil, then keep warm at 80-90°C for 3 hours, filter; Add 15-30 times more water to the slag, boil it, keep it warm at 85-95°C for 1.5 hours, filter, combine the filtrates...

Embodiment 2

[0039] Example 2 Preparation of freeze-dried powder injection

[0040] 1. Prescription

[0041] The ginseng effective part extract prepared in Example 1 6g

[0042] The Radix Ophiopogon japonicus effective fraction extract prepared in Example 1 0.6g

[0043] Accessories 100g

[0044] Add water for injection to 500ml

[0045] 2. Preparation method

[0046] Accurately weigh the above-mentioned extracts of effective parts of ginseng and extracts of Ophiopogon japonicus, add water to dissolve them under aseptic conditions, and set aside. In addition, weigh the calculated excipients (the excipients are commonly used excipients for powder injections) and place them in a sterile container, add water to dissolve. The two solutions were fully mixed under gentle stirring, and water was added to make up to 500-1000ml. After being filtered and sterilized by a microporous membrane, it is divided into sterilized freeze-dried vials, 2-20ml / bottle, freeze-dried, plugged and capped.

Embodiment 3

[0047] Example 3 Preparation of freeze-dried powder injection

[0048] 3. Prescription

[0049] The ginseng effective fraction extract prepared in Example 1 24g

[0050] The Radix Ophiopogon japonicus effective fraction extract prepared in Example 1 0.6g

[0051] Accessories 150g

[0052] Add water for injection to 1000ml

[0053] Prepared according to the method of Example 2.

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PUM

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Abstract

A composite Chinese medicine for treating cataract, visual fatigue and optic atrophy is prepared from ginseng and ophiopogon root. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating eye diseases, specifically, a pharmaceutical composition prepared from traditional Chinese medicines ginseng and Radix Ophiopogon japonicus as raw materials and its use, belonging to the field of traditional Chinese medicines. Background technique [0002] Cataract is the clouding of the lens in the eye from transparent to opaque, which prevents light from entering the eye and affects vision. The initial turbidity has little effect on vision, and then gradually aggravates, significantly affecting vision and even blindness. Cataract is the leading cause of blindness. About 20 million people in the world are blind due to cataract, and another 100 million cataract patients need surgery to restore vision. In most African and Asian countries, cataract accounts for at least half of the blind people . According to the results of our survey, cataract is also the most important eye disease tha...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K9/00A61P27/02A61P27/12
Inventor 曾雁鸣银海孙继林
Owner CHENGDU DIKANG PHARMA INST
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