[0038] Implementation case
[0039] Let the human body sleep in the cabin and make it quiet, and measure the unheated body temperature with the temperature measuring instrument 4b. Generally, the body temperature is generally maintained at 36-37°C due to the constant maintenance of function. Its self-regulation is maintained through a certain cycle. When the ambient temperature changes, the body temperature cycle, that is, the time spent in each cycle also changes, and is displayed as the state of body temperature regulation.
[0040] The measured body temperature is read into the control board 3 for FFT analysis, and then its period is set. Although the cycle will vary greatly depending on people and the environment, it is based on an orderly cycle of a few minutes on the surface and ten minutes in the depth as a general goal. In addition, FFT is the meaning of fast Fourier transform, which refers to what kind of frequency components are contained in the signal, and how many such components are contained in a fast and effective calculation method. This method was invented in 1965. The reciprocal of the frequency expressed in Hz is the time it takes for one cycle of the sine wave.
[0041] We learned in the second Stokes problem of fluid mechanics that the phase of thermal energy is similar to fluid energy, and the transmission of vibrational energy depends on its period and amplitude. When the period of the additional vibration energy coincides with the natural vibration number of the object, the transmitted energy increases due to the resonance phenomenon. Then, the heating devices 1a to 1d are turned on (ON) and off (OFF) to periodically heat the skin temperature in the same cycle and in the same phase. The rectal temperature began to rise rapidly with the skin temperature.
[0042] Generally speaking, the heat transfer conditions in the body vary greatly according to different environmental factors. The skin surface reacts sensitively to changes in the environment, that is, the temperature of the heating device. Through blood vessel activity, sweating, etc., heat or store heat inside the human body, so that the deep body temperature maintains a certain temperature. The deep temperature and skin temperature are slower in heat transfer and not easy to dissipate heat. Therefore, the cycle of self-discipline thermoregulation also tends to become larger.
[0043] At this time, the human body is taken as a system, the temperature cycle of the skin is taken as the input waveform, and the cycle of the deep temperature change is taken as the output waveform, and the transfer function of heat transfer in the body is obtained. The transfer function is a function of the relationship between the input and output of the signal transfer system. It is a function that expresses the changes in amplitude and phase between the input and output signals of the transfer system as the heating object with respect to the frequency.
[0044] The magnitude of the transfer function and the magnitude of the gain are represented by the vertical axis. Because the rectal temperature gradually attenuates with respect to the skin, its value is represented by a negative sign. At this time, it can be considered that the absolute value of the amplitude or gain in the transfer function has the maximum period, and the resonance frequency of the skin temperature change and the deep temperature change, that is, the heat energy added to the skin vibratingly is effectively transferred to the body.
[0045] During the same period as this cycle, the surface temperature of the heating device is changed and heated. When there are multiple peaks of the amplitude or the absolute value of the gain in the transfer function, that is, when there are multiple resonant peaks, the temperature is selected to be close to the skin temperature change period for heating. If the resonance frequency changes during the heating process, imitate its period to change the heating period. When selecting the resonance period, the heating period of the heating device is arbitrarily changed. When this periodic change is manifested by the periodic change of skin temperature, and when it is manifested by the periodic change of deep temperature, find its response time at this time. The period of the formant can be selected, that is, the time taken to be close to one period.
[0046] If the deep temperature reaches the set temperature, adjust the period, range and phase of the heating device according to the period and range of each body temperature change to maintain a certain temperature. When controlling the temperature rise in the deep part, the heat of the heating device can be turned OFF. However, sometimes the temperature is too low. At this time, the heat of the heating device must be maintained, and its cycle and the resonant frequency of the transfer function or the cycle of the skin temperature change into opposite phases. To increase the temperature of the deep part in a short period of time, it is necessary to increase the amplitude of the heating cycle, that is, the temperature of the heating device.
[0047] During heating or maintaining a certain state, it is necessary to set a safety range that does not burden the human body. When it is about to exceed this range, adjust by reducing the amplitude or blowing air to the head. The safe range refers to, for example, that the heart rate is below 150 beats per minute, the skin temperature is below 43°C, blood pressure and blood oxygen saturation do not change in peacetime as the standard, and carefully based on the physical condition of the person being heated Make settings.
[0048] figure 2 It is a data display graph before using the present invention. It shows the actual data after the human body is warmed without using the present invention with 40°C as the deep temperature target. image 3 Is the operation flow chart of the present invention, Figure 4 It is the effect display diagram after using the present invention and Figure 5 It is also an effect display diagram after using the present invention, showing the data obtained after using the present invention to warm the human body. In addition, in figure 2 , Figure 4 with Figure 5 The heating shown in refers to the heating in the state where no anesthetic is used. The tympanic membrane and rectum indicate the deep temperature, and the chest indicates the skin temperature. and also, figure 2 The set temperature in represents the surface temperature of the heating device. The cabin refers to the temperature in the cabin, that is, the temperature of the air near the human body.
[0049] Without using the invention for heating figure 2 In the early stage of warming, sweating and breathing become urgent, and the self-discipline function that suppresses the rise of deep body temperature starts to be activated. At the same time, blood flow increases due to the expansion of blood vessels, which leads to an increase in the ability to dissipate heat outside the body and a decrease in the heat transfer rate inside the human body. The rectal temperature, which is equivalent to the deep temperature, also increases. At this time, if the heating device or the surface temperature rises, the skin temperature rises too much, and there is a risk of burns. Therefore, the temperature of the heating device cannot be increased too quickly.
[0050] The temperature gradually rises after more than 1 hour, and the heart rate at this time changes to about 200 beats per minute, which may cause a burden on the cardiopulmonary function. After more than 2 hours, the rectal temperature finally rose to a temperature range close to 40°C, which is effective for cancer treatment. After the warming, the subject who was the subject of heating fell into severe heat stroke and would still feel quite tired after 2 days.
[0051] Figure 4 Is the data obtained after using the present invention. In this figure, you can’t see the image figure 2 In that way, a temporary drop in deep body temperature caused by the constant maintenance function of deep body temperature that appeared at the beginning of warming. According to the self-regulation cycle of body temperature, the heating device generates arbitrary and periodic changes and starts heating. Although the skin temperature changes periodically, it has been maintained below the safe range of 43°C, and the rectal temperature has reached 39°C. The heart rate is below 130 beats per minute where the burden on cardiopulmonary function is small. After the warming, the subject quickly recovered to their usual physical condition.
[0052] Figure 5 Shown in is the data when using the present invention and further improving the amplitude in the heating cycle of the heating device, that is, the surface temperature. Within about 30 minutes after the start of heating, adjust the heating device ON-OFF with 5 minutes or about 3.3mHz as a heating cycle. After 30 minutes, the heart rate can be observed to increase all of a sudden. Therefore, a fan must be used to exhaust the hot air in the cabin within 30 seconds. In the next 80 minutes, a heating cycle of 2 minutes, which is about 8.3mHz, is used. Warm up. Until the final rectal temperature reaches about 40°C.
[0053] At this time, the heart rate, blood pressure, and skin temperature are continuously maintained within a safe range. After the warming is over figure 2 The symptoms of heatstroke that I had seen disappeared, and there was no sense of fatigue or fatigue the next day. These indicators of the period or amplitude of the temperature change indicate that the body temperature of the deep part of the human body can be controlled safely and quantitatively even without anesthesia.
