Developing method for Chinese medicine compound secondary new medicine

Abstract

The present invention is secondary development process of compound Chinese medicine. The secondary development process includes the following steps: 1. selecting old recipe or proved recipe in use for long term, performing the medicine component analysis, recognizing the compound Chinese medicine recipe on the Chinese medicinal material level, and merging and decreasing medicine materials; 2. performing the analysis of medicine material components chemically and with fingerprints, and performing component identification and classifying; 3. proposing new recipe; 4. performing chemical component and fingerprint analysis of the medicine materials in new recipe, and determining the new production process; and 5. designing recipe proportioning by means of homogeneous design scheme, performing relevant pharmacodynaical and pharmacological experiments, and comparing the experiment results to determine the optimal recipe.

Description

technical field

[0001] The invention relates to a method for developing a new traditional Chinese medicine, in particular to a method for secondary new drug development through research on the compatibility of traditional Chinese medicines under the guidance of modern Chinese medicine theories. Background technique

[0002] Traditional Chinese medicine compound is the essence of traditional Chinese medicine. Suikan natural medicine extracts are widely used in the alternative treatment of disease drug treatment. Influenced by holistic medication and macroscopic treatment concepts, traditional Chinese medicine treatment cannot be well integrated into the modern drug treatment system, nor can it fully explain the exact material basis of drug action from the perspective of components, which interferes with the development and internationalization of traditional Chinese medicine. , hindered the further development of traditional Chinese medicine. Since Chinese materia medica is ...

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