Aescin medicine composition and its prepn process and use
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- WUHAN AIMIN PHARMA
- Publication Date
- 2007-03-21
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Abstract
Description
technical field
[0001] The invention belongs to the field of medicaments, and in particular relates to a escin pharmaceutical composition, a preparation method and an application thereof. Background technique
[0002] Aescin, also known as aescinic acid, is a general term for total saponins, β-aescin or isoescin, which are extracted from the seeds of Aesculus in the family Aesculus. At present, total aescin sodium (Totalescin) sodium is mostly used clinically, mainly containing 4 main components. According to the national standard of my country, it is named as aescin A (that is, escin I in Japan) according to the peak sequence of liquid chromatography. a ), aescin B (escin I b ), Aescin C (isoescin I a ) and aescin D (isoescin I a ). Aescin A and B are β-type aescins, their structure is basically the same, but with C 21 -Hydroxyl ester-forming organic acids are different, which are crotonoleic acid or angelic acid, which are anti-isomers of each other, so aescin A and ...