Aescin medicine composition and its prepn process and use

The technology of aescin and its composition is applied in the pharmaceutical composition of aescin and its preparation field, which can solve the problems of complex preparation process, etc., and achieve the effects of simple production process, improved curative effect, and excellent synergistic effect
CN1931176AActive Publication Date: 2007-03-21WUHAN AIMIN PHARMA

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
WUHAN AIMIN PHARMA
Publication Date
2007-03-21

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Abstract

The present invention relates to aescin medicine composition and its preparation process and use. The aescin product of purity over 90 % may be compounded with medicine carrier to form composition with obvious synergistic effect, reduced stimulation of aescin on blood vessels and muscles, and obviously raised effects of diminishing inflammation, antagonizing effusion, improving blood circulation, etc. The composition features its less stimulation, high safety, high treating index, etc.
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Description

technical field

[0001] The invention belongs to the field of medicaments, and in particular relates to a escin pharmaceutical composition, a preparation method and an application thereof. Background technique

[0002] Aescin, also known as aescinic acid, is a general term for total saponins, β-aescin or isoescin, which are extracted from the seeds of Aesculus in the family Aesculus. At present, total aescin sodium (Totalescin) sodium is mostly used clinically, mainly containing 4 main components. According to the national standard of my country, it is named as aescin A (that is, escin I in Japan) according to the peak sequence of liquid chromatography. a ), aescin B (escin I b ), Aescin C (isoescin I a ) and aescin D (isoescin I a ). Aescin A and B are β-type aescins, their structure is basically the same, but with C 21 -Hydroxyl ester-forming organic acids are different, which are crotonoleic acid or angelic acid, which are anti-isomers of each other, so aescin A and ...

Claims

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