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Preparing process of Jade-screen total polyose

A technology of jade screen and total polysaccharide, applied in the field of extracting total polysaccharide, can solve the problems of reducing the use efficiency and filtration effect of filter membrane, destroying the integrity of compound traditional Chinese medicine, increasing the burden of waste disposal, etc., so as to improve the overall utilization rate and efficiency. and effect, the effect of reducing the discharge of waste

Inactive Publication Date: 2011-07-20
TIANJIN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of Yupingfeng polysaccharides are in the research stage and have not yet been industrialized. There is a lack of medicines or health products related to Yupingfeng total polysaccharides on the market.
[0005] The existing method of extracting polysaccharides is mainly based on traditional boiling and alcohol precipitation, and the boiling temperature is mostly 100°C. Due to the high boiling temperature, there are more non-polysaccharide components in the extract, which will affect the quality of the product
Moreover, most of the extracts are subjected to membrane filtration steps such as ultrafiltration without proper treatment, so that some impurities such as proteins in the extract will pollute the filter membrane to a certain extent, reducing the use efficiency and filtration effect of the filter membrane.
[0006] The existing extraction of active ingredients such as astragalus, atractylodes, and polysaccharides in windproof is extracted from single -flavored medicinal materials, which not only wastes energy and resources, but also destroys the overallness of compound Chinese medicine
In addition, the existing Yupingfeng products, such as Yupingfeng Oral Liquid, only process the supernatant after the medicinal materials are boiled and alcoholized to make related products, which wastes resources and reduces the utilization rate of traditional Chinese medicines, and increases the cost of traditional Chinese medicine. Reduce the burden on waste disposal in the later stage, and may cause certain pollution to the environment

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0036] The preparation method of Yupingfeng total polysaccharide is as follows:

[0037] Slice the three herbs of Radix Astragali, Atractylodes Rhizoma Atractylodes Rhizome and Fangfeng respectively and grind them into powders, mix the three medicinal powders according to the ratio of Astragalus Radix 1-3, Atractylodes Rhizoma Atractylodes Rhizoma 1-2, and Fangfeng 1-2 in parts by mass, and mix the three medicinal powders evenly The mixture is placed in a three-necked bottle, 5 to 10 times the mass of water is added, soaked for 0.5 to 12 hours, and then leached at 60 to 85°C for 2 to 5 hours. After cooling to room temperature, filter, and extract the filter cake twice with water according to the above method, and combine the filtrate to obtain the extract, which can be processed by any one of the following three methods:

[0038] (1) Add 0.8 to 1.8 g / L (amount of clarifying agent solution added per liter of extracting liquid) of B clarifying agent solution to the combined extr...

Embodiment 1

[0043]Sloped astragalus, atractylodes, and windproof three -flavored medicines and crushed it to the end. Take 600g of astragalus powder, leukotus and windproof powder each 200g each, place it in a trio bottle, add 5000ml of water, soak for 0.5 hours, and then immerse in 60 ° C under 60 ° C. Lift 2 hours. After cooling to room temperature, filter and extract the filter cake twice with water according to the above method. Combine the filtrates, add 0.8g / L (the amount of clarifier solution added per liter of leach solution) B clarifier solution wherein. After 2 hours of heat preservation at 80°C, add 0.4g / L (amount of clarifier solution added per liter of extract) of A clarifier solution, and then keep warm at 80°C for 2 hours. Centrifuge and take the supernatant. The supernatant obtained in the above steps is filtered with a membrane, and the filtrate with a molecular weight less than 50,000 is collected and concentrated to obtain a concentrated solution with a relative densi...

Embodiment 2

[0045] Sloped astragalus, atractylodes, and windproof three -flavored medicines and crushed it to the end. Take 400g of astragalus powder, 400g of Atractylodes powder, 200g of windproof powder, place it in a triangular bottle, add 6000ml of water, soak for 2 hours, and then under 65 ℃ under 65 ℃ Leach for 3 hours. After cooling to room temperature, filter and extract the filter cake twice with water according to the above method. Combine the filtrates, add 1.8g / L (the amount of clarifier solution added per liter of leach solution) B clarifier solution wherein. After 2 hours of heat preservation at 80°C, add 0.9g / L (amount of clarifier solution added per liter of extract) of A clarifier solution, and keep warm at 80°C for 2 hours. Filter and take the supernatant. The supernatant obtained in the above steps is filtered with a membrane, and the filtrate with a molecular weight less than 50,000 is collected and concentrated to obtain a concentrated solution with a relative densi...

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PUM

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Abstract

The present invention discloses preparation process of Jade-screen total polyose. The preparation process includes the following steps: water extract Jade-screen mixture and filtering the leached liquid; adding clarifier solution into the filtrate and filtering or centrifuging to obtain the supernatant; membrane filtering to collect filtrate of molecular weight smaller than 50 KD and concentrating and alcohol precipitating the filtrate; taking the precipitate and water washing and drying to obtain the Jade-screen total polyose. The process maintains the integrity of the compound Chinese medicine preparation, reduces the entraining of non-polyose components, has high product purity and is suitable for industrial production. Treating the leached liquid with clarifier can reduce the contamination of protein and other impurity on the filtering membrane and raise the membrane filtering efficiency and effect.

Description

technical field [0001] The invention relates to a method for extracting total polysaccharides from Yupingfeng. Background technique [0002] The compound traditional Chinese medicine "Yupingfeng San" is a representative prescription for strengthening the body and eliminating evils. It originated from "Danxi Xinfa" in the Yuan Dynasty. The theory of "strengthening the body and eliminating pathogenic factors" in traditional Chinese medicine has a long history in the prevention and treatment of infectious diseases. [0003] "Yupingfeng Powder" is composed of Astragalus, Atractylodes Rhizoma Atractylodes Rhizome and Radix Fangfeng. This party is like a barrier against external evils to the human body, so it is called Yupingfeng. Modern research has proved that the important component polysaccharides in the active ingredients of Yupingfeng powder have a good effect on improving the immune function of the human body. [0004] According to reports in recent years, astragalus pol...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K36/481C08B37/00A61P37/04
Inventor 张黎明赵朝张小利孙茜谢伟光刘莹
Owner TIANJIN UNIV OF SCI & TECH