Amphiphilic molecular modules and constructs based thereon

a technology of applied in the field of amphiphilic molecular modules and constructs based thereon, can solve the problems of a large amount of effort and continues to be spent on devising

Inactive Publication Date: 2004-02-19
COVALENT PARTNERS LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Since that time a tremendous amount of effort has been, and continues to be, spent on devising practical applications for this new-found ability to work directly with the atom.

Method used

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  • Amphiphilic molecular modules and constructs based thereon
  • Amphiphilic molecular modules and constructs based thereon
  • Amphiphilic molecular modules and constructs based thereon

Examples

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Embodiment Construction

[0200] Reagents were obtained from Aldrich Chemical Company and VWR Scientific Products. All reactions were carried out under nitrogen or argon atmosphere unless otherwise noted. Solvent extracts of aqueous solutions were dried over anhydrous Na.sub.2SO.sub.4. Solutions were concentrated under reduced pressure using a rotary evaporator. Thin layer chromatography (TLC) was done on analtech Silica gel GF (0.25 mm) plates or on Machery-Nagel Alugram Sil G / UV (0.20 mm) plates. Chromatograms were visualized with either UV light, phosphomolybdic acid, or KMnO.sub.4. All compounds reported were homogenous by TLC unless otherwise noted. HPLC analyses were performed on a Hewlett Packard 1100 system using a reverse phase C-18 silica column. Enantiomeric excess was determined by HPLC using a reverse phase (l)-leucine silica column from Regis Technologies. All .sup.1[H] and .sup.13[C] NMR spectra were collected at 400 MHz on a Varian Mercury system. Electrospray mass spectra were obtained by Sy...

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Abstract

The present invention relates to the preparation of synthons that are used to form modules that, in turn, are used to form two-dimensional close-packed planar arrays, referred to as nanomembranes. In a presently preferred embodiment, a nanomembrane herein constitutes a filter.

Description

[0001] This invention is related to the fields of organic chemistry and nanotechnology. In particular, it relates to materials and methods for the construction of amphiphilic modules and the formation of nanomembranes, from the modules.BACKGROUND OF THE INVENTON[0002] In 1959, Richard Feynman addressed a meeting of the American Physical Society with a talk titled "There's Plenty of Room at the Bottom." Professor Feynman, drawing on his own fascination with biology ("Biological systems can be exceedingly small . . . but they are active; they manufacture substances, they walk around; . . . and they do all kind of marvelous things--all on a very small scale."), predicted that amazing feats of man-made miniaturization would be realized in the not too distant future.[0003] Twenty-six years later, K. Eric Drexler wrote a book entitled "Engines of Creation" in which he described nanotechnology as "the knowledge and means for designing, fabricating and employing molecular scale devices by t...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): C07D259/00C07D471/22
CPCC07D259/00C07C211/50C07C215/78C07C215/80C07C229/46
Inventor KARPISHIN, TIMOTHY B.KRIESEL, JOSHMERRILL, GRANTBIVIN, DONALD B.SMITH, THOMAS H.EDELSTEIN, MARTIN STUART
Owner COVALENT PARTNERS LLC
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