Medicinal association of a biguanine and a carrier, for example metformin and arginine

a biguanine and carrier technology, applied in the field of medicine combination, can solve the problem of low bioavailability
US20070265349A1Inactive Publication Date: 2007-11-15INOPHARM

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
INOPHARM
Publication Date
2007-11-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

A medicinal combination for the treatment of diabetes, in particular of type 2 diabetes, combining a biguanide, in particular an N-dimethylbiguanide, as a first medicament, and an agent for transporting the said biguanide, as a second medicament, said combination comprising: e [sic] a therapeutically active quantity of the biguanide f [sic] and a quantity of transporting agent, previously determined to potentiate the therapeutic activity of the biguanide according to (a).
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Description

[0001] This is a Divisional of application Ser. No. 10 / 465,997, filed Oct. 3, 2003, which in turn is a National Stage Application of PCT / FR01 / 04235, filed Dec. 31, 2001, which in turn claims the benefit of French Patent Application No. 00 / 17332, filed Dec. 29, 2000. The entire disclosure of the prior applications is hereby incorporated by reference herein in their entirety.FIELD OF THE INVENTION

[0002] The present invention relates to a medicinal combination of two active principles, having, jointly, a complementary and / or synergistic action, this being for the treatment of diabetes, in particular of type 2 diabetes.

[0003] The expression “complementary action” is intended to mean the pharmacological action of two different compounds making it possible to act on the same pathology via two respectively different pharmacological mechanisms, for example the combined use of two antidiabetic agents, such as a biguanide and a sulfonylurea.

[0004] The expression “synergistic action” is int...

Claims

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