Use of Flumazenil in the Production of a Drug for the Treatment of Alcohol Dependency
a technology of alcohol dependency and flumazenil, which is applied in the field of pharmaceutical compositions, can solve the problems of increasing the cost and duration of treatment, delirium tremens, and inconvenience for patients, and achieves the effects of reducing side effects, short time period, and effective elimination of alcohol dependency symptoms
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Treatment of Patients with Flumazenil Sequentially and at Low Dose
1.1 Experimental Protocol
[0029]64 alcoholics (51 males and 13 females) voluntarily entered a treatment program to discontinue the use of alcohol. Said patients were provided the appropriate information and the corresponding informed consent form was obtained
from them. The patients were warned not to drink alcohol the morning on which the treatment was to be carried out to enable better evaluation of the withdrawal symptoms.
[0030]Table 1 summarizes the characteristics of the patients treated associated with alcohol use.
TABLE 1Characteristics of the patientsassociated with alcohol useMeanSDMinimumMaximumAge (years)42.710.22075Age at the beginning of daily24.610.2671alcohol use (years)Daily units of alcohol intake24.915.4473γ-glutamyl transpeptidase159.1227.2121.230(GGT)Corpuscular volume97.86.472111(RBC)Number of previous detoxifications1.61.205[SD: Standard deviation]NOTE:85% consumed alcohol daily and 39.1% consumed b...
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