Systems and methods for assessing vasculature health and blood clots
a vasculature health and blood clot technology, applied in the field of systems and methods for assessing vasculature health and blood clots, can solve the problems of ischemic stroke, blood flow sudden occlusion, and cell energy loss
Inactive Publication Date: 2017-10-12
MAKAHA MEDICAL
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- Abstract
- Description
- Claims
- Application Information
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Benefits of technology
Enables informed decision-making for clot removal, reducing the risk of hemorrhagic events and improving treatment efficacy by providing real-time data on clot composition and vasculature health.
Problems solved by technology
The most common cause of cerebrovascular disease is narrowing of the major arteries supplying blood to the brain, resulting in thrombogenic disease or sudden occlusion of blood flow, which if large enough results in ischemic stroke.
A shortage of blood in the cerebral tissue leads to the deletion of metabolites such as oxygen and glucose, which in turn causes depletion of energy stores of the cells.
A problem encountered with these approaches is that the composition of the clot is undetectable in situ, while the efficacy of these approaches is dependent in part on the clot composition.
This can lead to inconsistent results as well as failure to properly treat the clot.
In addition, in cerebrovascular disease, the vitality of the vasculature distal to the clot is compromised once the clot lodges in place.
Once blood flow is restored after clot removal, such blood flow could potentially cause a hemorrhagic event, which means the vessel can bleed out and burst open.
Currently, surgeons do not have adequate knowledge of the vasculature downstream of the clot and therefore cannot accurately assess the risk of clot removal.
However, these attempts to date have been unsuccessful.
Additionally, relying on MRI is very expensive and requires relatively complex mathematical models.
Method used
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Embodiment Construction
[0056]The present invention provides a system for determining the health or condition of the vasculature distal of the blood clot. This aids the physician in assessing the effect of removal of the blood clot from the vessel. The present invention also provides a system for determining the type of blood clot. This enables the physician to assess the best mode of treatment of the blood clot. These two systems can be used independently or alternatively can be used together. That is, it is contemplated that only one of the systems is utilized so the user measures only one of the parameters, i.e., either health of vasculature or type of clot. However, it is also contemplated that both systems be utilized so the user can determine both parameters. These systems are described in detail below.
Vasculature Determination
[0057]Turning first to the system for determining the health or condition of the vasculature, this system is illustrated in FIGS. 1-8, with FIGS. 1-5 illustrating an embodiment...
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A system and method for determining a pH level of blood in a vessel of a patient including a flexible elongated member configured and dimensioned for insertion in the vessel of the patient, a sensor positioned at the distal portion of the elongated member, and a connector connecting the elongated member to an indicator. The sensor measures the pH level of blood downstream of the blood clot. A system and method are also provided for determining a density of a blood clot in a vessel of a patient for subsequent selection of a treatment method. The system includes a sensor positioned at the distal portion of the elongated member, and a connector connecting the elongated member to an indicator, wherein the sensor determines the density of the blood clot and the indicator provides an indication of the density of the clot.
Description
[0001]This application claims priority from provisional application Ser. No. 61 / 718,107, filed Oct. 24, 2012, the entire contents of which are incorporated herein by reference.BACKGROUNDTechnical Field[0002]This application relates to a system for determining the health of the vasculature to enable the surgeon to assess the advisability of blood clot removal. This application also relates to a system for identifying the composition of a blood clot in a vessel to enable the physician to scientifically determine the clot makeup to determine the best course of treatment for the clot.Background of Related Art[0003]Cerebrovascular disease refers to diseases of the brain caused by vascular abnormalities which result in abnormal cerebral blood flow. The most common cause of cerebrovascular disease is narrowing of the major arteries supplying blood to the brain, resulting in thrombogenic disease or sudden occlusion of blood flow, which if large enough results in ischemic stroke.[0004]Clots ...
Claims
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IPC IPC(8): A61B5/02A61B5/1455A61B8/00A61B8/12A61B8/08A61B5/145A61B5/00
CPCA61B5/02007A61B5/14539A61B5/14551A61B5/14503A61B8/445A61B5/6851A61B8/12A61B8/085A61B8/0891A61B5/6852A61B5/14542A61B8/0833A61B8/4494A61B8/461A61B8/467A61B8/485A61B8/5223G16H50/30
InventorLEVINE, MARC-ALAN
OwnerMAKAHA MEDICAL