Swallowable capsule, system and method for measuring gastric emptying parameters

Abstract

Embodiments provide devices, systems and methods for measuring a gastric emptying (GE) parameter (GEP). Many embodiments provide a swallowable capsule having three electrodes one covered by a coating which remains in the stomach but is degraded in the small intestine (SI). The electrodes are coupled to circuitry such that when the capsule is in the stomach, current flow occurs between the first two electrodes generating a first signal and in the SI current flow occurs between the second and now uncovered third electrode generating a second signal. These two signals can be transmitted and analyzed externally or by an internal controller to determine a GEP e.g., GE time. The patient may wear an external device configured to receive and analyze the signals to determine GE time. Embodiments of the invention may be used to diagnose gastroparesis and provide patient's information on when to eat meals or administer insulin after eating.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a continuation of U.S. patent application Ser. No. 16 / 006,093, filed Jun. 12, 2018, now U.S. Pat. No. ______; which claims the benefit of priority of U.S. Provisional Patent Application Ser. No. 62 / 518,246, filed Jun. 12, 2017; the contents of which are fully incorporated herein by references for all purposes.BACKGROUND OF THE INVENTION1. Field of the Invention[0002]Embodiments described herein relate to devices, systems and methods for measuring physiologic parameters of the gastro-intestinal system. More specifically embodiments of the invention relate to devices, systems and methods for measuring gastric emptying parameters such as gastric emptying time.[0003]There are a number of conditions which can affect the proper digestion and function of the gastro-intestinal tract of a human or other mammal. One of them, gastroparesis, also known as delayed gastric emptying, is a condition characterized by multiple symptoms,...

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