32 results about "ANTIPSORIATICS" patented technology

Sorption agent for treating diseases and conditions associated with an increased concentration of at least one inflammation mediator, preferably cytokine, comprises a porous sorption matrix with a neutral, hydrophobic surface, an average pore size of 11-20 nm and an average particle size of 75-150 mu m. Independent claims are also included for: (1) a sorption device comprising at least one sorption agent; and (2) an extracorporeal perfusion device comprising at least one sorption agent. ACTIVITY : Antibacterial; Immunosuppressive; Hepatotropic; Antiinflammatory; Virucide; Antiarthritic; Antirheumatic; Gastrointestinal-Gen; Antipsoriatic. Test details are described but no results given. MECHANISM OF ACTION : None given.

The invention provides formulations containing sanguinarine, chelerythrine or chelidonine or their salts or extracts containing them, mixed with suitable vehicles and / or excipients, for the treatment of common skin warts and verrucas, anal and vulvar warts and psoriatic plaques.

The invention discloses application of acetamide in anti-inflammatory drugs, immunomodulators and anti-psoriasis drugs. Acetamide can strongly resist inflammation, IL-17F and TNF-alpha levels in serumare lowered remarkably, the expression of IL-22 is improved, showing that the acetamide has functions of anti-inflammation and immune suppression. The acetamide can adjust both nonspecific immunity and specific immunity, can increase a serum antibody generation level, increase levels of IL-1beta and IL-6 in serum and decrease the level of TNF-alpha in serum, and can increase the thymus coefficient remarkably. The acetamide can resist psoriasis strongly, and can decrease IL-17F and IL-23 in serum, wherein IL-17F and IL-23 are typical cell factors of psoriasis, and the acetamide can improve cells of the epidermis, spinous layer and dermis.

The invention relates to a medicine for treating psoriasis, belongs to the technical field of traditional Chinese medicines, and aims at solving the technical problem that a medical for treating psoriasis with remarkable curative effect and small side effect is provided. The technical scheme provided by the invention is as follows: the medicine comprises the raw materials in parts by weight as follows: 8-15 parts of the fruit of Chinese wolfberry, 10-16 parts of radix paeoniae alba, 6-15 parts of radix sophorae flavescentis, 8-20 parts of the root of red-rooted salvia, 6-12 parts of Scutellaria baicalensis, 15-35 parts of Oldenlandia diffusa, 6-12 parts of American ginseng, 6-15 parts of radix pseudostellariae, 6-12 parts of Angelica sinensis, 10-30 parts of oyster, 10-30 parts of concha haliotidis, 10-30 parts of concha haliotidis threads, 6-10 parts of blood heat added lithospermum, 6-10 parts of indigo naturalis, 8-15 parts of blood dry added prepared rehmannia root, 8-20 parts of Polygonum multiflorum, 10-30 parts of blood stasis added Caulis Spatholobi, 10-14 parts of madder, 0.1-3 parts of pseudo-ginseng powder, 6-10 parts of heat toxin added Coptis chinensis, 6-13 parts of damp-heat type added jasmine and 8-15 parts of semen coicis. The medicine provided by the invention has good effect for treating various types of psoriasis.

The invention discloses a pharmaceutical composition for treating or alleviating dermatopathy. The pharmaceutical composition is composed of traditional Chinese medicines such as raw rehmannia root, clerodendroa cyrtophyllum and the like, and can be made into dosage forms such as pills, tablets, capsules and the like according to clinical needs. The pharmaceutical composition has a very excellent effect of treating or alleviating psoriasis.

The invention relates to a Chinese medicament for treating psoriasis, and belongs to the field of Chinese medicaments for treating dermatosis. The invention aims to provide the Chinese medicament with good effect and quick response. The Chinese medicament is prepared from the following raw materials: alkanet, thick dried rehmannia root, radix pseudo-ginseng, suberect spatholobus stem, lucid ganoderma, Chinese angelica, lalang grass rhizome and the like. The Chinese medicament has the effects of strengthening body resistance and banking up root, tonifying qi and nourishing blood, activating blood and dissolving stasis, and clearing heat, cooling blood and moisturizing skin, and has the advantages of obvious effect, exact medicinal effect and quick response.

The invention discloses a nano-system which takes PLGA (polylactic-co-glycolic acid)-coated anti-psoriasis pharmaceutical camptothecin as a core of the nano-system, coats PAMAM (polyamidoamine) on the surface of PLGA as a shell of the nano-system and adopts an emulsification solvent volatilization method to prepare camptothecin, and furthermore, oleic acid (OA) is used for modification to obtain a core-shell nano-drug delivery system after surface modification. Further, hydroxypropyl methylcellulose (HPMC) is taken as a matrix to prepare camptothecin nano-gel (CPT-PPO gel). CPT-PPO gel modified by oleinic acid can significantly improve pharmaceutical skin absorption and detention without increasing skin permeation, thereby not increasing the amount of a medicament entering blood circulation, effectively reducing systemic toxicity of the medicament and being an excellent camptothecin local treatment new dosage form.

The invention relates to a Chinese medicament for treating psoriasis, and belongs to the field of Chinese medicaments for treating dermatosis. The invention aims to provide the Chinese medicament with good effect and quick response. The Chinese medicament is prepared from the following raw materials: glabrous greenbrier rhizome, Chinese angelica, radix pseudo-ginseng, lalang grass rhizome, red paeony root, lucid ganoderma, root of rehmannia and the like. The Chinese medicament has the effects of strengthening body resistance and banking up root, tonifying qi and nourishing blood, activating blood and dissolving stasis, clearing heat and detoxicating, and drying dampness and relieving itching, and has the advantages of obvious effect, exact medicinal effect and quick response.

The invention discloses a method for preparing a Chinese medicament for treating psoriasis vulgaris. The Chinese medicament is characterized in that: the Chinese medicament is prepared from the following components: 30 to 60g of rhubarb powder, 10 to 30g of arnebia root, 10 to 30g of licorice powder, 30 to 60g of turmeric powder, 30 to 60g of radix scutellariae powder, 50 to 80g of zinc oxide powder, 10 to 30g of salicylic acid, 10 to 50g of menthol crystal, 10 to 50g of sulfur powder, 10 to 20g of borneol powder, 0.1 to 1g of retinoic acid, and 10ml of azone, and the Chinese medicament is a topical tincture. The Chinese medicament for treating the psoriasis vulgaris has the effects of clearing heat and releasing toxin, diminishing inflammation and easing pain, and clearing damp and relieving itching, and has good treatment effect on the psoriasis vulgaris.

The invention relates to a medicine for treating psoriasis. The medicine is prepared from the following traditional Chinese herbs as raw medicinal materials in a certain parts by weight: 25-35 parts of radix rehmanniae, 8-15 parts of the root bark of the peony tree, 8-12 parts of root of common peony, 5-10 parts of peach kernel, 6-12 parts of safflower carthamus, 12-18 parts of angelica sinensis, 28-35 parts of caulis spatholobi, 12-18 parts of radix isatidis, 10-15 parts of folium isatidis, 25-32 parts of rhizoma smilacis glabrae, 8-12 parts of radices lithospermi, and 6-15 parts of raw sophora flower. All the raw medicinal materials in the parts by weight are added with water to submerge the medicine to be heated till a boiling point and then decocted for 30 minutes each time and two times in total; the decocted liquid for the two times is combined and filtered to obtain the decoction in the invention. The medicine disclosed by the invention is low in side effect, stable in treatment effect, and capable of prolonging the catabatic period.

The invention discloses a method for synthesizing an important anti-psoriasis medicament anthralini-fused ring derivatives, and synthesizes a plurality of novel anthralini-fused ring derivatives. The method comprises the steps of taking anthralini (dihydroxy anthracene phenols, 1,8,9-dithranol) as an initial raw material, allowing the initial raw material to react with 1-phenylethynyl Fischer carbene compounds and obtaining four types of novel anthralini-fused ring derivatives through continuous addition / cyclization reaction and oxidation-demetalization reaction. The method utilizes the multi-reactivity of the 1-phenylethynyl Fischer carbene compounds and subjects the 1-phenylethynyl Fischer carbene compounds and anthralini to successive multi-step reaction under mild conditions so as to obtain the anthralini-fused ring derivatives which are difficult to synthesize by conventional organic synthesis methods or can be obtained only through complex synthesis steps. The method has the advantages of mild conditions of synthesis reaction, simple convenient operation, readily available raw materials and high efficiency.