The invention discloses a method for predicting passenger demand on airline routes, which includes the following steps: Step 1: Obtain data on factors affecting demand in the civil aviation market, including: the total amount of air passenger flow in two places, the capacity of airports in two places, the distance between two places, and the fare level , Whether there is a high-speed rail connection; Step 2, establish a forecasting model of passenger demand in the two places: passenger demand in the two places = f (total air passenger flow in the two places, airport capacity in the two places, distance between the two places, fare level, whether there is a high-speed rail connection ), among which, the passenger demand of the two places is positively correlated with the total air passenger flow of the two places and the distance between the two places, and the passenger demand of the two places is negatively correlated with the distance between the two places, the fare level and whether there is a high-speed rail connection; step 3, step 1 The obtained factor data affecting the demand of the civil aviation market is brought into the passenger demand forecast model of the two places established in step 2, and the passenger demand result of the route is calculated. The invention can comprehensively consider the market and economic development status, and effectively predict the demand of airline passengers.