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The application provides a preparation method of astaxanthin cordyceps militaris fine tablets, comprising the following steps: subjecting cordyceps militaris fruiting bodies to supercritical CO2 extraction treatment to separate a cordyceps militaris terpene component; mixing Haematococcus pluvialis powder and edible vegetable oil, adding the cordyceps militaris terpene component and rosemary extract, and cooling and forming to obtain an astaxanthin-cordyceps militaris terpene blend; crushing the residue after extraction, adding purified water and a composite enzyme preparation to perform enzymolysis to obtain an enzymolysis liquid; adding a chitosan quaternary ammonium salt solution, centrifuging after flocculation, vacuum drying, and crushing to obtain cordyceps militaris active powder; mixing and granulating raw materials to obtain granulation particles; uniformly mixing the granulation particles with xylitol and microcrystalline cellulose, and pressing into tablets; and placing the tablets in a coating machine for coating. The application realizes efficient retention of active ingredients, improvement of safety and stability of product quality through the cooperation of multiple technologies such as supercritical CO2 extraction, enzymolysis flocculation, low-temperature fluidized bed granulation and hot melt coating.