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Filter for removing fibrinogen, filter device for removing fibrinogen, and method of removing fibrinogen using the same

A technology of fibrinogen and filter medium, applied in the field of filter medium for removing fibrinogen, filter device for removing fibrinogen and use of the device to remove fibrinogen

Inactive Publication Date: 2007-10-17
SEKISUI CHEM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the method described in JP-A No. 2000-309539 above, proteins contained in blood plasma, such as albumin, are also simultaneously removed by adsorption, so there are samples obtained by this method that cannot carry out the removal of such substances. Questions about the blood test to be tested

Method used

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  • Filter for removing fibrinogen, filter device for removing fibrinogen, and method of removing fibrinogen using the same
  • Filter for removing fibrinogen, filter device for removing fibrinogen, and method of removing fibrinogen using the same
  • Filter for removing fibrinogen, filter device for removing fibrinogen, and method of removing fibrinogen using the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Take a plurality of non-woven fabrics made of polyethylene terephthalate with an average fiber diameter of 1.8 μm (the loop density is 40 g / m 2 ), each piece of cloth is punched out with a diameter of 15 mm, and these cloths are stacked, from which 1.0 g of a sample is weighed. The sample was loaded into a 10-mL syringe woven by JMS, and pressurized to compress its volume to 4 mL.

Embodiment 2

[0045] Take a plurality of non-woven fabrics made of polyethylene terephthalate with an average fiber diameter of 1.8 μm (the loop density is 40 g / m 2 ), each piece of cloth is punched out with a diameter of 15 mm, and these cloths are stacked, from which 1.0 g of a sample is weighed. The sample was loaded into a JMS woven 10-mL syringe, which was then pressurized to compress its volume to 3.2 mL.

Embodiment 3

[0047] Take a plurality of non-woven fabrics made of polyethylene terephthalate with an average fiber diameter of 1.8 μm (the loop density is 40 g / m 2 ), each piece of cloth is punched out with a diameter of 15 mm, and these cloths are stacked, from which 1.0 g of a sample is weighed. The sample was filled into a JMS woven 10-mL syringe, which was then pressurized to compress its volume to 2.4 mL.

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Abstract

It is intended to provide a filter for removing fibrinogen and a filter device for removing fibrinogen and a method of removing fibrinogen using the same by which a serum sample not affecting blood examination data can be quickly prepared from plasma. A filter for removing fibrinogen from plasma which is made of a fiber mass, microparticles or a porous polymer capable of adsorbing fibrinogen, has a surface area of 0.5 m<2> / g or larger and a porosity of 85% or lower.

Description

technical field [0001] The present invention relates to a method for removing fibrinogen contained in serum or plasma and a member used in the method. Background technique [0002] Blood tests are widely used in laboratory tests to diagnose disease. Many blood tests are serum tests, and the serum required for these tests is usually obtained by coagulating blood collected in a blood test container, from clots with different specific gravity (that is, containing fibrin and blood cell groups) The serum is separated from a gel-like substance in the mixture and then centrifuged. For blood coagulation, a coagulation-promoting component is added to the blood test container, and absorbable inorganic materials are conventionally used as the coagulation-promoting component, but recently enzymes such as thrombin and venom are also used to reduce the clotting time, thereby reducing the number of test results obtained The necessary time, improve convenience. [0003] On the one hand, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/48B01J20/26
Inventor 宇治义则户川胜也五十川浩信
Owner SEKISUI CHEM CO LTD