Nano Pd catalyst and its preparation and application

Abstract

Disclosed is a nano-palladium catalyst which is polymer loading nano-palladium catalyst produced by water-soluble inorganic palladium salt and water-soluble macromolecule in low-carbon alcohol at 60-90 DEG C. The preparation process is simple, activity of the catalyst is high and the catalyst can be used repeatedly. When using the catalyst to preparation biphenyl, solvent can be water, organic base can be replaced by inorganic base, the process is simplified and avoids more waste gas, liquid and solid, dosage of catalyst is few, purity of product is not less than 99.5 % and yield is not less than 95 %.

Description

1. Technical field [0001] The invention relates to a catalyst for organic synthesis and its preparation method and application, in particular to a nano-palladium catalyst, its preparation method and its application in coupling reaction preparation of biphenyl compounds. 2. Background technology [0002] Biphenyl compound is an important organic intermediate, which is widely used in the production of many fine chemicals such as materials, medicine, pesticides, and daily chemicals. The usual synthetic method is to use substituted phenylboronic acid and substituted halogen (bromine and iodine) benzene as raw materials, under the catalysis of transition metal palladium complexes, in organic solvents such as triethylamine, diethylamine, tetrahydrofuran, N, N-di Complete (Suzuki Coupling Suzuki coupling reaction) in methyl formamide, this method technology is mature, but the use and discharge etc. of metal palladium and ligand cause environmental pollution in the production proces...

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Problems solved by technology

The usual synthetic method is to use substituted phenylboronic acid and substituted halogen (bromine and iodine) benzene as raw materials, under the catalysis of transition metal palladium complexes, in organic solvents such as triethylamine, diethylamine, tetrahydrofuran, N, N-di Complete (Suzuki Coupling Suzuki coupling reaction) in methyl formamide, this method technology is mature, but the use and discharge etc. of metal palladium and ligand cause environmental pollution in the production process; And metal palladium black can pollute product so that make It is difficult to purify the product; in addition, another disadvantage of this method is the use of a large amount of organic solvents, which need to be recycled, which increases equipment investment and operating costs, and pollutes the environment, causing harm to workers' health

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