Nanometer aquogel with both pH and temperature sensitivity and its preparation process
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- CHINA PHARM UNIV
- Publication Date
- 2008-06-11
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to the field of environment-sensitive polymer nanomaterials, in particular to pH- and temperature-sensitive N-isopropylacrylamide nano-hydrogels and a preparation method thereof. Background technique
[0002] Poly N-isopropylacrylamide (PNIPAM) hydrogel is a widely studied class of temperature-sensitive materials. This type of hydrogel has a volume phase transition at its lowest critical solution temperature (LCST: 32°C): When the external temperature is lower than LCST, PNIPAM has hydrophilic properties, swells in aqueous solution, and contains a large proportion of water inside; when the external temperature is higher than LCST, PNIPAM becomes hydrophobic, and the internal water is squeezed out, and its volume changes. small.
[0003] CN01129696.8, CN01129694.1 disclose the preparation method of porous temperature-sensitive poly(N-isopropylacrylamide) hydrogel. CN03144329.X discloses a copolymerization gel of N-isopropylacryla...