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Medicine for treating insomnia and preparation method thereof

A technology for drugs and APIs, applied in the field of drugs for treating insomnia and their preparation, can solve the problems of being unsuitable for modern large-scale production, unsuitable for diversification of diseases, tolerance dependence, etc. No toxic side effects, enhanced protective effect

Inactive Publication Date: 2008-06-18
王信锁
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, some old prescriptions are mostly used in the Chinese patent medicines for the treatment of insomnia, which are no longer suitable for the diversified diseases of today, let alone modern large-scale production. Moreover, these Chinese patent medicines for the treatment of insomnia mostly use important calming minerals such as cinnabar etc., while treating insomnia, it will cause a certain degree of damage to the human body.
All existing western medicines all have following problems: (1) almost all hypnotics, long-term continuous use all can produce tolerance and dependence
It should be said that there is no hypnotic drug that fully meets these conditions so far, so it is an important topic of modern medical research to develop ideal sedative-hypnotic drugs and preparations that meet the above conditions as much as possible.

Method used

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  • Medicine for treating insomnia and preparation method thereof
  • Medicine for treating insomnia and preparation method thereof
  • Medicine for treating insomnia and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0046] The preparation of the capsule of embodiment 1 medicine of the present invention

[0047] Filling the active components in this formula into capsule shells of different materials can be made into special capsules such as hard capsules, soft capsules and enteric-coated capsules.

[0048] (1) Take the following traditional Chinese medicines as raw materials:

[0049] 2.5 parts by weight of amber, 8 parts by weight of jujube seed,

[0050] 7 parts by weight of Shouwu vine, 6 parts by weight of Albizia juniper, set aside;

[0051] (2) adding 95% ethanol to the weighed amber, jujube seed, Shouwu vine, and Albizia Julibrissin to carry out reflux extraction, reclaim the extract, and filter the extract through a 120-mesh stainless steel screen;

[0052] (3) Recover ethanol from the extract of step (2), and dry at 45°C to obtain dry extract 1 for subsequent use;

[0053] (4) Weigh 4.5 parts by weight of mother-of-pearl, 5 parts by weight of dragon tooth, 2 parts by weight of ...

Embodiment 2

[0057] The tablet preparation of embodiment 2 medicines of the present invention

[0058] (1) Take the following traditional Chinese medicines as raw materials:

[0059] 1 part by weight of amber, 6 parts by weight of wild jujube seed,

[0060] 6 parts by weight of shouwu vine, 8 parts by weight of acacia bark, set aside;

[0061] (2) adding 50% ethanol to the weighed amber, jujube seed, shouwu vine, and acacia bark to carry out reflux extraction, reclaim the extract, and filter the extract through a 120-mesh stainless steel screen;

[0062] (3) Recover ethanol from the extract of step (2), and dry at 45°C to obtain dry extract 1 for subsequent use;

[0063] (4) Weigh 2 parts by weight of mother-of-pearl, 2 parts by weight of dragon tooth, 0.5 part by weight of polygala, and 0.5 part by weight of Acorus calamus, add water to decoct, and filter the extract through a 120-mesh stainless steel screen;

[0064] (5) adding 50% ethanol to the extract of step (4) for alcohol precip...

Embodiment 3

[0068] The preparation of the pill of embodiment 3 medicines of the present invention

[0069] The main active components in this formula are made into pill-shaped preparations, which are divided into ordinary (large and small) pill-shaped preparations and small droplet pill preparations. Different binders can be used to make honeyed pills, water pills, paste pills, wax pills and concentrated pills.

[0070] (1) Take the following traditional Chinese medicines as raw materials:

[0071] 4 parts by weight of amber, 10 parts by weight of wild jujube seed,

[0072] 10 parts by weight of Shouwu vine, 10 parts by weight of Albizia juniper bark, set aside;

[0073] (2) adding 75% ethanol to the weighed amber, jujube seed, Shouwu vine, and acacia bark to carry out reflux extraction, reclaim the extract, and filter the extract through a 120-mesh stainless steel screen;

[0074] (3) Recover ethanol from the extract of step (2), and dry at 50°C to obtain dry extract 1 for subsequent ...

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Abstract

The invention discloses a pharmaceutical composition for treating insomnia and process for preparation, wherein the composition is prepared from amber 1-4 weight parts, wild or spiny jujuba seed 6-10 weight parts, tuber of multiflower knotweed 6-10 weight parts, albizia bark 6-10 weight parts, ruby mica 2-6 weight parts, draconic dentes 2-6 weight parts, polygala root 0.5-3 weight parts, acorus gramineus soland 0.5-3 weight parts, rehamnnia root 1-4 weight parts, coptis root 1-4 weight parts, Chinese angelica root 0.5-3 weight parts, and poria cocos wolf 0.5-3 weight parts.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a medicine for treating insomnia and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. Background technique [0002] At present, with the continuous progress of society, the continuous development of science and technology, the competition is increasingly fierce, forcing people's pace of life to speed up, people's mental pressure is also increasing, and the phenomenon of lack of sleep is becoming more and more common. Various diseases such as insomnia, depression, neurosis, and schizophrenia caused by lack of sleep and excessive mental stress have risen sharply, and due to the increasing incidence, they are called "invisible health killers." According to statistics, there are currently about 16 million patients with insomnia, depression and other mental diseases in the country, and about 250,000 people die by suicide every year. The in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/888A61K36/804A61K36/725A61K36/718A61K36/704A61K36/69A61K36/48A61K36/232A61K36/076A61K35/56A61K35/10A61K35/02A61P25/20A61K35/618
Inventor 王信锁
Owner 王信锁
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