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Preparation of compound puerarin

A technology of puerarin and preparations, applied in the field of compound puerarin preparations, can solve problems such as poor efficacy, achieve the effect of reducing the amount of medication and shortening the treatment cycle

Inactive Publication Date: 2008-10-22
安康北医大制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the use of only a single puerarin in the prior art, the effect of treating coronary heart disease and cerebral embolism is not good enough

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] The compound puerarin preparation contains 10 g of puerarin, 0.1 g of ginkgolide A (Ginkgolide A), 0.5 g of mannitol and 5 g of sodium bicarbonate. During use, carry out freeze-drying according to the freeze-drying process, make the powder injection that each bottle contains puerarin and ginkgolide A (GinkgolideA) respectively 0.1g, 0.001g.

Embodiment 2

[0016] The compound puerarin preparation contains 5g of puerarin, 2.5g of ginkgo extract (EGb), 0.5g of mannitol and 10g of polyvinylpyrrolidone. During use, carry out freeze-drying according to the freeze-drying process, make the powder injection that each bottle contains puerarin and ginkgo leaf extract (EGb) and is respectively 0.1g, 0.05g.

Embodiment 3

[0018] The compound puerarin preparation contains 5g of puerarin, 0.2g of ginkgolide B (Ginkgolide B), 0.5g of mannitol and 3g of hydroxypropyl-β-cyclodextrin. During use, it is freeze-dried according to the freeze-drying process, and the specifications are made into injections containing puerarin and 0.1 g and 0.004 g of ginkgolide B (Ginkgolide B) respectively in each bottle.

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PUM

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Abstract

A Chinese medicine "Compound kakonein" for dilating blood vessel contains kakonein and ginkgo extract in weight ratio of 10:((0.1-10). Its advantages are high curative effect and short course of treatment.

Description

technical field [0001] The invention relates to a pharmaceutical preparation for treating coronary heart disease and cerebral embolism, in particular to a compound puerarin preparation. Background technique [0002] Puerarin preparation is a blood vessel dilating drug, and Ginkgo biloba L. is a relic plant that survived on the earth during the ice age, and is known as a "living fossil". China is the birthplace of ginkgo, and its resources account for about 70% of the world's total. In the early 1960s, Dr. Willar Schwabe (Weimar Schwabe) in Germany obtained Ginkgo biloba extract (EGb761) from Ginkgo biloba leaves for the first time, which has significant curative effect for treating cardiovascular and cerebrovascular diseases and nervous system diseases, and has no obvious side effects; Ginkgolide has important physiological activities such as significant anti-platelet activating factor (PAF). The currently clinically used puerarin injection is prepared according to the WS-...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/48A61K36/16A61K31/365A61P9/10
Inventor 徐世明高海郭书台王远清
Owner 安康北医大制药股份有限公司