Medicine for treating senescent arthritis

An arthritic, geriatric technique with applications in medicine

Inactive Publication Date: 2009-07-08
SHANDONG XUANZHU PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] At present, the use of curculigo, fairy spleen, rehmannia, cinnamon, Shichangpu, or curculigo, fairy spleen, rehmannia, cinnamon, Qingfengteng, Shichangpu, or curculigo, fairy spleen, rehmannia, cinnamon, Qingfeng The interaction and compatibility of rattan, Achyranthes bidentata, and Shichangpu, which are used to prepare medicines for treating senile arthritis, have not been reported yet

Method used

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  • Medicine for treating senescent arthritis
  • Medicine for treating senescent arthritis
  • Medicine for treating senescent arthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0124] Embodiment 1: the preparation of pharmaceutical tablet of the present invention

[0125] Curculigo 240g, Fairy Spleen 240g, Rehmannia glutinosa 300g, Cinnamon 120g, Shichangpu 180g

[0126] 1) take curculigo, celestial spleen, rehmannia glutinosa, cinnamon, calamus calamus of described weight portion, set aside;

[0127] 2) Add 8 times the amount of water to the weighed cinnamon and calamus calamus, soak for 2 hours, and steam distill for 6 hours to obtain volatile oil, collect the water extract, and clathrate the volatile oil with β-CD (weigh an appropriate amount of β-CD, add water to dissolve , kept at 50°C, slowly added volatile oil while stirring, stirred at high speed for 2 hours, refrigerated and stood for 24 hours, filtered, washed with an appropriate amount of water for the β-CD inclusion complex, and dried at room temperature), to obtain active ingredient A;

[0128] 3) Add curculigo, celestial spleen, rehmannia glutinosa, cinnamon and calamus, which have b...

Embodiment 2

[0130] Embodiment 2: the preparation of medicine capsule of the present invention

[0131] Curculigo 240g, Xianling spleen 240g, Rehmannia glutinosa 300g, Cinnamon 120g, Qingfengteng 240g, Shichangpu 180g

[0132] 1) take curculigo, celestial spleen, rehmannia glutinosa, cassia cinnamon, vine, and calamus of said weight portion, and set aside;

[0133] 2) Add 8 times the amount of water to the weighed cinnamon and calamus calamus, soak for 2 hours, and steam distill for 6 hours to obtain volatile oil, collect the water extract, and clathrate the volatile oil with β-CD (weigh an appropriate amount of β-CD, add water to dissolve , kept at 50°C, slowly added volatile oil while stirring, stirred at high speed for 2 hours, refrigerated and stood for 24 hours, filtered, washed with an appropriate amount of water for the β-CD inclusion complex, and dried at room temperature), to obtain active ingredient A;

[0134] 3) Add curculigo, celestial spleen, rehmannia glutinosa, cinnamon ...

Embodiment 3

[0137] Embodiment 3: the preparation of pharmaceutical granule of the present invention

[0138] Curculigo 240g, Fairy Spleen 240g, Rehmannia glutinosa 300g, Cinnamon 120g, Qingfengteng 240g, Achyranthes bidentata 180g, Shichangpu 180g

[0139] 1) Take curculigo, celestial spleen, Rehmannia glutinosa, cassia cinnamon, Cinnamon chinensis, Achyranthes bidentata, and calamus calamus of said weight portion, and set aside;

[0140] 2) Add 8 times the amount of water to the weighed cinnamon and calamus calamus, soak for 2 hours, and steam distill for 6 hours to obtain volatile oil, collect the water extract, and clathrate the volatile oil with β-CD (weigh an appropriate amount of β-CD, add water to dissolve , kept at 50°C, slowly added volatile oil while stirring, stirred at high speed for 2 hours, refrigerated and stood for 24 hours, filtered, washed with an appropriate amount of water for the β-CD inclusion complex, and dried at room temperature), to obtain active ingredient A; ...

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Abstract

The present invention pertains to the field of pharmaceutical technology, which discloses a drug for treating senile arthritis and the preparation method. The drug is mainly prepared by common curculigo rhizome, epimedium herb, radix rehmanniae preparata, cassia bark and grassleaf sweelflag rhizome, or common curculigo rhizome, epimedium herb, radix rehmanniae preparata, cassia bark, ovientvine and grassleaf sweelflag rhizome, or common curculigo rhizome, epimedium herb, radix rehmanniae preparata, cassia bark, ovientvine, twotooth achyranthes root and grassleaf sweelflag rhizome with certain mixing ratio by weight. The present invention can be made into any formulation which is acceptable clinically or on the pharmacy, while the oral preparation is preferential. The drug has the effects of nourishing yang and yin, activating blood circulation and dredging collaterals, which is used for the treatment of senile arthritis and the effect is significant.

Description

1. Technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a medicine for treating senile arthritis and a preparation method thereof. 2. Background technology [0002] Osteoarthritis is a chronic joint disease characterized by wear and tear of articular cartilage, and then involving subchondral bone, synovium, meniscus, ligaments and other joint internal and external structures, resulting in varying degrees of pathological changes. Clinically, it is mainly characterized by pain, swelling, and dysfunction of the affected joints, including limited mobility, difficulty in walking with weight bearing, and late hypertrophy and deformation. The course of the disease is characterized by recurrent attacks and chronic protraction. high. Because the disease generally occurs in the elderly, it is called senile osteoarthritis. As our country enters an aging country, this disease will continue to increase. [0003] Modern medicine ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/888A61K36/88A61K36/804A61K36/59A61K36/54A61K36/296A61K36/21A61P19/02
Inventor 黄振华
Owner SHANDONG XUANZHU PHARMA TECH CO LTD
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