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Cardiac and cerebral vascular disease treating medicine composition

A composition and medicine technology, applied in the field of medicine, achieves the effects of simple preparation process, lowering left ventricular end-diastolic pressure, and increasing myocardial blood supply

Inactive Publication Date: 2008-01-02
SHANDONG XUANZHU PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, the use of ginseng, notoginseng and trichosanthes or the interaction and compatibility of ginseng, notoginseng, trichosanthes and ginkgo biloba to prepare drugs for treating cardiovascular and cerebrovascular diseases has not been reported yet.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] Embodiment 1: the preparation of pharmaceutical tablet of the present invention

[0086] 1) 15 g of Radix Ginseng and 5 g of Panax notoginseng were extracted three times with ethanol back flow, the extraction time was 3 hours, 3 hours, and 2 hours respectively, and the amount of alcohol added was 12 times, 10 times, and 8 times respectively, and the extracts were combined and filtered. After filtration, the filtrate recovers ethanol until it has no alcohol smell, adds water to an appropriate amount (so that each 1ml is equivalent to 1.5g of the original medicinal material), stirs well, refrigerates for 24 hours, filters, and extracts the filtrate with water-saturated n-butanol 3 times, all adding 1 times Measure n-butanol, combine the n-butanol liquid, recover n-butanol under reduced pressure to a thick paste, and dry under reduced pressure to obtain dry extract A.

[0087] 2) Grind 15g of Trichosanthes trichosanthes, pass through a 20-mesh sieve, add 4 times the amou...

Embodiment 2

[0090] Embodiment 2: the preparation of pharmaceutical composition capsule of the present invention

[0091] 1) 15 g of Radix Ginseng and 5 g of Panax notoginseng were extracted three times with ethanol back flow, the extraction time was 3 hours, 3 hours, and 2 hours respectively, and the amount of alcohol added was 12 times, 10 times, and 8 times respectively, and the extracts were combined and filtered. After filtration, the filtrate recovers ethanol until it has no alcohol smell, adds water to an appropriate amount (so that each 1ml is equivalent to 1.5g of the original medicinal material), stirs well, refrigerates for 24 hours, filters, and extracts the filtrate with water-saturated n-butanol 3 times, all adding 1 times Measure n-butanol, combine the n-butanol liquid, recover n-butanol under reduced pressure to a thick paste, and dry under reduced pressure to obtain dry extract A.

[0092] 2) Grind 15g of Trichosanthes trichosanthes, pass through a 20-mesh sieve, add 4 t...

Embodiment 3

[0094] Embodiment 3: the preparation of pharmaceutical composition granule of the present invention

[0095] 1) 15 g of Radix Ginseng and 5 g of Panax notoginseng were extracted three times with ethanol back flow, the extraction time was 3 hours, 3 hours, and 2 hours respectively, and the amount of alcohol added was 12 times, 10 times, and 8 times respectively, and the extracts were combined and filtered. After filtration, the filtrate recovers ethanol until it has no alcohol smell, adds water to an appropriate amount (so that each 1ml is equivalent to 1.5g of the original medicinal material), stirs well, refrigerates for 24 hours, filters, and extracts the filtrate with water-saturated n-butanol 3 times, all adding 1 times Measure n-butanol, combine the n-butanol liquid, recover n-butanol under reduced pressure to a thick paste, and dry under reduced pressure to obtain dry extract A.

[0096] 2) Grind 15g of Trichosanthes trichosanthes, pass through a 20-mesh sieve, add 4 t...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases, its preparation process and use, wherein the composition is prepared mainly from ginseng, pseudo-ginseng, pericarpium trichosanthis and ginkgo leaf. The composition can be made into any clinically and pharmaceutically acceptable dose forms, preferably oral preparations.

Description

1. Technical field [0001] The invention relates to a pharmaceutical composition mainly composed of ginseng, notoginseng and trichosanthes, and ginkgo leaves as well as its preparation method and application, belonging to the technical field of medicine. 2. Background technology [0002] Cardiovascular and cerebrovascular diseases include coronary heart disease, angina pectoris, myocardial infarction, congestive pulmonary heart disease, ischemic encephalopathy, cerebral thrombosis, hypertension, hyperlipidemia, etc. The main cause of these diseases is that arteriosclerosis causes narrowing of the lumen and blockage of the pipeline, which leads to insufficient blood supply to the heart and brain, causing symptoms such as dizziness, dizziness, headache, and chest tightness. In severe cases, it can lead to stroke and myocardial infarction. Cardiocerebral ischemia affects energy metabolism, secondary to various changes such as lactic acid accumulation, calcium overload, and free ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/428A61P9/10
Inventor 黄振华
Owner SHANDONG XUANZHU PHARMA TECH CO LTD
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