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Traditional Chinese medicinal composition for treating children epilepsy and its preparation method

A composition and technology of traditional Chinese medicine are applied in the field of traditional Chinese medicine composition for treating epilepsy in children and the field of preparation thereof, and can solve the problems of withdrawn or irritable, children prone to seizures, slurred speech and the like

Active Publication Date: 2008-01-09
韩志强 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] (2) Variability: some children's epilepsy is changeable, and there may be different types of seizures at different periods
[0006] (3) Frustration: it is often an incomplete attack, that is, it does not show the whole process of the attack, but ends at a certain stage of the attack
[0008] (5) Adverse factors are easy to induce: children are prone to seizures under the influence of adverse factors (such as fever, irregular life, overeating, etc.)
[0009] (6) Periodicity: children with epilepsy who have not been systematically and regularly treated or who have frequent seizures (especially after a major seizure or a persistent state), and who cannot be controlled for a long time, have obvious changes in intelligence and personality, such as low intelligence, Silly, dull, naive, slurred speech, taciturn, withdrawn or irritable, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Add 80g of Radix Pseudostellariae, 80g of Poria cocos, 80g of Pinellia (manufactured) , 48g of orange, 120g of green fruit and 48g of Citrus aurantium (stir-fried with bran) and add 12 times the amount of water, extract 3 times, the first time is 3 hours, and the second time is 2 hours 1 hour for the third time, the filtrates were combined and concentrated to a thick paste with a relative density of 1.20 (70°C); 80g of Dannanxing, 48g of Gastrodia elata, 120g of Acorus calamus, 24g of amber, 24g of agarwood, 80g of Liushenqu (stir-fried with bran), Chuanxiong 48g and Notopterygium 48g are crushed into fine powder, sieved through 80 mesh, mixed with the above thick paste, crushed to make granules, dried at 80°C, crushed into 65 mesh powder, and packed into capsules.

Embodiment 2

[0022] Embodiment 2 Chinese medicine composition tablet of the present invention

[0023] Add 15g of Radix Pseudostellariae, 15g of Poria cocos, 15g of Pinellia (manufactured) , 200g of orange, 480g of green fruit and 200g of Citrus aurantium (stir-fried with bran) and add 10 times the amount of water, extract twice, the first time is 3 hours, and the second time is 2 hours , combined the filtrates, concentrated to a thick paste with a relative density of 1.40 (70°C); crushed Dannanxing 320g, Gastrodia elata 200g, Iris calamus 20g, amber 100g, agarwood 3g, Liushenqu (stir-fried with bran) 15g, chuanxiong 200g and notopterygium 5g into a fine powder, passed through a 80-mesh sieve, mixed with the above-mentioned thick paste, crushed, 260g of crystalline cellulose and 70g of compressible starch were mixed with the fine powder, wet granulated with 95% ethanol, dried, and added with low-substituted hydroxypropyl Base cellulose 50g, appropriate amount of talcum powder, compressed i...

Embodiment 3

[0024] Embodiment 3 Chinese medicine composition soft capsule of the present invention

[0025] Add 320g of Radix Pseudostellariae, 320g of Poria cocos, 320g of Shui Pinellia (manufactured), 5g of orange red, 20g of green fruit, and 5g of Citrus aurantium (stir-fried bran) with 8 times the amount of water, extract once for 3 hours, and concentrate the filtrate to a relative density of 1.02( 70°C) thick paste; grind Dannanxing 15g, Gastrodia elata 5g, Jiujiechangpu 480g, amber 3g, agarwood 100g, Liushenqu (stir-fried with bran) 320g, Chuanxiong 5g and notopterygium 200g into fine powder, pass through a 80-mesh sieve, and Mix the above thick paste, pulverize it, add an appropriate amount of beeswax, and mix it with a colloid mill for 30 minutes. The mixture is made into 1000 grains by automatic rotary bag rolling, and dried for 24 hours at a temperature of 20°C and a relative humidity of 52%. Washed with ethanol and dried under the above conditions for 48 hours to obtain.

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PUM

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Abstract

The invention is concerned with the Chinese traditional medicine combination for treating children epilepsy, consists of arisaema cum bile, gastrodia elata, pseudostellaria root, Tuckahoe, pinellia, chrysoidine, acorus gramineus soland, Chinese olive, amber, agilawood, stir-frying with bran, fructus aurantii immaturus, hemlock parsley, angelica polyclada and / or acceptable carrier pharmacy. The invention is also concerned with the preparation method of the Chinese traditional medicine combination.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating epilepsy in children and a preparation method thereof. Background technique [0002] Pediatrics refer to the period from the fetus to the adolescent, which is divided into the fetal period (the child is in the mother's body, about 280 days), the neonatal period (from birth to 28 days after birth), the infancy period (before one year old), There are seven stages: early childhood (after 1 year old to before 3 years old), preschool age (3 years old to 6 years old), school age (6 years old to 13 years old), and adolescence (juvenile period, 13 years old to 18 years old). Epilepsy in these seven age groups is collectively referred to as pediatric epilepsy. The prevalence of children is higher, about 10 to 15 times that of adults, and 20% to 30% of them still have recurrent seizures despite treatment and become intrac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P25/08A61K35/10
Inventor 兰玉岐
Owner 韩志强
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