The application belongs to an
animal model, and aims to solve the technical problems that the evaluation method of the current Skinner box experimental data lacks a systematic experimental paradigm and evaluation means, and lacks related parameters, and provides an
experimental animal learning and
memory disorder model, a construction method and application. The traditional chronic social
frustration model experiment process is optimized, the learning and
memory disorder model of the mouse is stably induced, and the obtained
experimental animal learning and
memory disorder phenotype is obvious, and the diversity of stress-
related disorder animal models is enriched. The learning and memory ability of the animal is evaluated by the Skinner box, the learning and memory related evaluation means is expanded, and new data support is provided for the construction and evaluation of the acute violent
stress induced learning and memory disorder
animal model.