Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Compound pharmaceutical composition, preparation method and use of the same

A composition and compound technology, applied in the field of compound pharmaceutical composition and its preparation, can solve the problems of short action time, easy rebound of antipyretic effect, slow action, etc.

Active Publication Date: 2010-06-02
BEIJING DABEINONG ANIMAL HEALTH TECH
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing antipyretic drugs have slow action and short action time, and the antipyretic effect is easy to rebound, which cannot meet the clinical needs

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Compound pharmaceutical composition, preparation method and use of the same
  • Compound pharmaceutical composition, preparation method and use of the same
  • Compound pharmaceutical composition, preparation method and use of the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] prescription:

[0024] Diclofenac Sodium 2g

[0025] Naproxen 4g

[0026] N-methyl-2-pyrrolidone 60ml

[0027] Antioxidant amount

[0028] Add water for injection to 100ml

[0029] Preparation:

[0030] 1. Take the prescribed amount of N-methyl-2-pyrrolidone, add diclofenac sodium, stir to dissolve; add naproxen, stir to dissolve.

[0031] 2. Take an appropriate amount of water for injection, add antioxidant, stir to dissolve.

[0032] 3. Combine 1 and 2, adjust the pH value to 5-8, dilute to 100ml with water for injection, and filter through a membrane.

[0033] 4. Potting, steam sterilization at 100°C for 30 minutes, ready to serve.

Embodiment 2

[0035] prescription:

[0036] Diclofenac Sodium 1g

[0037] Naproxen 10g

[0038] N-methyl-2-pyrrolidone 80ml

[0039] Antioxidant amount

[0040] Add water for injection to 100ml

[0041] Preparation:

[0042] 1. Take the prescribed amount of N-methyl-2-pyrrolidone, add diclofenac sodium, stir to dissolve; add naproxen, stir to dissolve.

[0043] 2. Take an appropriate amount of water for injection, add antioxidant, stir to dissolve.

[0044] 3. Combine 1 and 2, adjust the pH value to 5-8, dilute to 100ml with water for injection, and filter through a membrane.

[0045] 4. Potting, steam sterilization at 100°C for 30 minutes, ready to serve.

Embodiment 3

[0047] prescription:

[0048] Diclofenac Sodium 10g

[0049] Naproxen 1g

[0050] N-methyl-2-pyrrolidone 80ml

[0051] Antioxidant amount

[0052] Add water for injection to 100ml

[0053] Preparation:

[0054] 1. Take the prescribed amount of N-methyl-2-pyrrolidone, add diclofenac sodium, stir to dissolve; add naproxen, stir to dissolve.

[0055] 2. Take an appropriate amount of water for injection, add antioxidant, stir to dissolve.

[0056] 3. Combine 1 and 2, adjust the pH value to 5-8, dilute to 100ml with water for injection, and filter through a membrane.

[0057] 4. Potting, steam sterilization at 100°C for 30 minutes, ready to serve.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a medical composition used for the febrifuge, analgesia and anti-inflammation of the animals, a preparation method and the application thereof. The medical composition comprises diclophenac sodium and naproxen. The weight proportion of the diclophenac sodium and the naproxen is 1:10-10:1 while the preferred scope is 1:5-5:1. The invention also provides the preparation method of the injection of the medical composition and the application in the control of livestock and poultry pyrexia. The invention has more thorough febrifuge effect than any single preparation with the characteristics of fast action and uneasy rebound relative to the oral preparation.

Description

[0001] This application is a divisional application of 200610076344.6, the filing date of the original application: 2006.4.21, the name of the invention: a compound pharmaceutical composition and its preparation method and use technical field [0002] The invention belongs to antipyretic, analgesic and anti-inflammatory drugs for livestock and poultry, in particular to a compound pharmaceutical composition composed of diclofenac sodium, naproxen or barbiturate and a preparation method thereof. Background technique [0003] When livestock and poultry are attacked by bacteria, viruses, and mycoplasma, most of the clinical symptoms are accompanied by inflammatory symptoms (fever, pain), which affect the normal diet, activities and healthy growth of the demand. Therefore, whether it is from the perspective of animal welfare or animal production, anti-inflammatory (antipyretic, analgesic) is necessary while administering antibacterial and antiviral drugs. [0004] In my country, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/196A61P29/00A61K31/192
CPCY02A40/70
Inventor 田玲莫云刘彤郭致君王海良布仁阿古达木
Owner BEIJING DABEINONG ANIMAL HEALTH TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com