Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medical hydrogel wound dressing and preparation method thereof

A wound dressing and hydrogel technology, which is used in medical science, bandages, absorbent pads, etc., can solve the problems of waste of medical supplies such as hydrogel wound dressings, weak ability to maintain the moist environment of wounds, and increased workload of medical staff. , to achieve the effect of promoting wound healing, no cytotoxicity and acute toxicity, and saving medical supplies

Active Publication Date: 2013-10-23
SUZHOU UNIV
View PDF1 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this preparation method and the resulting hydrogel film have the following disadvantages: 1. The swelling degree of the hydrogel wound dressing obtained by the preparation method is only about 1900%, and its ability to absorb wound exudate and maintain a wound moist environment is relatively low. Weak, it needs to be replaced within 1-2 days of clinical use, which not only increases the workload of medical staff for frequent replacement, but also causes waste of medical supplies such as hydrogel wound dressings, and more importantly, frequent replacement of dressings will cause wound infection , Secondary injury, especially the situation of large area and high exudation skin wound; ②The preparation method includes cold and hot cycle treatment steps, which consumes a lot of energy and also increases the complexity of the process

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medical hydrogel wound dressing and preparation method thereof
  • Medical hydrogel wound dressing and preparation method thereof
  • Medical hydrogel wound dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A method for preparing a medical superabsorbent hydrogel wound dressing comprises the following steps in sequence:

[0024] (1) batching, sodium polyacrylate and polyvinyl alcohol (PVA) are mixed according to weight ratio 20~30: 2~6, then add double distilled water, be made into the solution that mass concentration is 27%;

[0025] (2) Film casting: the above solution is heated and dissolved to become a homogeneous mixture aqueous solution, and the above solution is poured into a film-making dish to cool down and form a mold with a thickness of 1 mm;

[0026] (3) Radiation processing: use electron accelerator β electrons to carry out radiation cross-linking and grafting, the conditions are: during radiation synthesis, the voltage is 2.45MeV, the current is 14mA, the dose rate is 15kGy / time, and the dose is 30-90kGy;

[0027] (4) The hydrogel samples prepared by radiation were sterilized and stored in a refrigerator at 4°C for later use.

[0028] The hydrogel wound dres...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

An improved hydrogel wound dressing and its preparation is disclosed. The ingredients used in the dressing are PAAS of 20~30 wt %, PVA of 2~6 wt % and water of 64~78 wt %. The hydrogel wound dressings were formed by dissolution, casting films, radiation synthesis and sterilization. Compared with conventional hydrogel dressings the improved dressings displayed an enhanced degree of swelling. Cell growth factors may be incorporated into the dressings to be released slowly in the wound.

Description

technical field [0001] The invention relates to a dressing and a preparation method thereof, in particular to a superabsorbent medical hydrogel wound dressing and a preparation method thereof. Background technique [0002] At present, the treatment of traumatic wound surfaces and wounds such as burns, scalds, and wounds in clinical medicine generally adopts wet therapy, that is, wrapping wound dressings on the wound surface to keep the wound in a moist state for a long time to reduce pain and accelerate wound healing. heal. Existing wound dressings mainly include three types, i.e. universal type, biological type and composite type. Among them, composite type wound dressing mainly refers to hydrogel wound dressing, that is, a certain concentration of high molecular polymer such as polyvinyl alcohol, polyacrylic acid, etc. Sodium, polyethylene oxide, polyvinylpyrrolidone, polyacrylic acid, partially neutralized polyacrylic acid, polyethylene oxide, polyacrylamide and other so...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/24A61L15/44
CPCA61L15/60A61L2300/414A61L15/44
Inventor 杨占山饶志高岳凌杨淑琴朱南康
Owner SUZHOU UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com