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Periodically degrading type tear drainage rebuilding system

A technique for tear fluid and lacrimal sac, which is applied in the field of new lacrimal duct stents, can solve problems such as failure to effectively promote the repair of lacrimal duct mucosal damage, and achieve the effects of stable and reliable lacrimal duct support, good elastic retraction, and a simple and quick method.

Inactive Publication Date: 2012-09-05
吴文灿 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to overcome the shortcomings of the current lacrimal duct supports that cannot effectively promote the repair of lacrimal duct mucosal damage, to more fully drain tears, to avoid as much as possible secondary lacrimal duct damage caused by the second-stage removal, and to better fix the support Problem, the present invention provides a lacrimal drainage reconstruction system integrating the lacrimal canaliculus, common lacrimal duct, lacrimal sac and nasolacrimal duct. The implantation method is simple and quick, and it can not only provide stable and reliable lacrimal duct support function, and has good "tear pump" function, "sustained drug release" function, lacrimal sac pus drainage and lacrimal duct injury repair function. The internal fixation of the lacrimal duct is reliable and can be degraded and absorbed regularly without the need for secondary removal

Method used

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  • Periodically degrading type tear drainage rebuilding system
  • Periodically degrading type tear drainage rebuilding system
  • Periodically degrading type tear drainage rebuilding system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Example 1. As figure 1 , figure 2 As shown, the present invention integrates lacrimal canaliculus (1) (2), common lacrimal duct (3), lacrimal sac (4), and nasolacrimal duct (5). Larger than the lacrimal duct of the human body, the outer diameter of the upper lacrimal canaliculus (1) is 1.5-3.5mm, the standard is 2.0mm, the inner diameter is 1.0-2.5mm, the standard is 1.0mm, the outer diameter of the lower lacrimal canaliculus (2) is 1.5-3.5mm, the standard is 2.5mm, The inner diameter is 1.0-2.5mm, the standard is 1.5mm, the angle (α) between the upper and lower canaliculus is 30°-55°, the standard is 45°; the upper canaliculus (1) and the lower canaliculus (2) merge into the common lacrimal duct ( 3), the length of the common lacrimal duct (3) is 0.5-8.5 mm, the standard is 2.0 mm, the outer diameter is 2.0-4.0 mm, the standard is 2.5 mm, the inner diameter is 1.0-3.0 mm, the standard is 1.5 mm, the angle between the common lacrimal duct and the lower lacrimal canali...

Embodiment 2

[0014] Example 2. If figure 1 , figure 2 As shown, the present invention includes the whole lacrimal duct, wherein the lacrimal sac (4) has a longitudinal diameter of 7.2 to 24.5 mm, a standard of 10.5 mm, a transverse diameter of 5.0 to 15.0 mm, a standard of 8.5 mm, an anteroposterior diameter of 3.0 to 7.5 mm, and a standard of 5.0 mm. The human lacrimal sac is slightly larger, and the lacrimal sac wall (13) is extremely thin, with a wall thickness of 15-50um, and the standard is only 25um. Because the present invention is made of PDO, it has a good flexibility ratio and a certain "memory" function. After implantation, it is closely attached to the inner wall of the lacrimal sac of the human body, and expands and contracts with the lacrimal sac of the human body through biomechanical transmission to achieve " Tear pump" function.

Embodiment 3

[0015] Example 3. As figure 1 , figure 2 , image 3As shown, the present invention is a hollow pipe structure in the form of mesh micropores, wherein the micropores of the common lacrimal duct (8) have a diameter of 25~65um, the standard is 50um, and the micropores of the wall of the lacrimal duct wall (9) have a diameter of 10~30um, the standard is 25um, The diameter of micropores (14) on the bottom wall of the lacrimal sac is 80-120um, and the standard is 100um. And the bottom of the lacrimal sac (6) is a concave structure with the top of the arc upward, the vertical height from the top of the arc to the bottom corners (7) at both ends is 2.5 mm, and the center is continuous with the nasolacrimal duct (5). When the medicine or tears enter the lacrimal sac (4) through the "lacrimal sac expansion" and siphon action, part of it accumulates here, and then automatically leaks through the above-mentioned micropores, or under the action of the "tear pump" to the surroundings and...

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Abstract

The invention relates to a tear drainage reconstruction system that can be regularly degraded. The reconstruction system is made by adopting polydioxanone (PDO) that is a degradable polymeric biomaterial. The system comprises an upper lacrimal duct part, a lower lacrimal dust part, a main lacrimal duct, a concave dacryocyst part and a nasolacrimal duct part. The system has good flexibility, certain elasticity, extensibility, breaking strength and compression strength performance and is a lamella micro-porous tubular structure that integrates stable nasolacrimal duct supporting function, 'tears pump' function, dacryocyst drainage function, 'drug control-release' function, the function of accelerating the fade-away of chronic inflammation of a lacrimal duct and the repairing function of mucous membrane injury of the lacrimal duct together. The reconstruction system has the advantages that an implanting method is a simple and convenient, the fixation in the lacrimal duct is the stable and reliable and the iatrogenic lacrimal duct injury cannot appear, the regular degradation can be realized without secondary take-out and the reconstruction system is suitable for various lacrimal duct obstruction diseases and has high curative ratio of the lacrimal duct obstruction, especially, the reconstruction system has the stable and reliable medium-to-long term effect. The tears drainage reconstruction system currently is the only perfect material for high-degree lacrimal duct reconstruction that combines the physiological drainage of the tears with the pathological mechanism of lacrimal injury repair.

Description

Technical field: [0001] The invention relates to an implant for ophthalmic surgery, which provides a novel lacrimal duct support that can be degraded regularly for reconstructing lacrimal fluid drainage in patients with lacrimal duct obstruction. Background technique [0002] Lacrimal duct obstruction is a common disease in ophthalmology, especially chronic dacryocystitis is often referred to as a "time bomb" next to the eyeball. When the cornea and eyeball are traumatized, suppurative corneal ulcer, suppurative endophthalmitis and other serious complication. In recent years, with the continuous improvement of people's demand for quality of life, the concept of "minimally invasive surgery for lacrimal duct obstruction" has been generally accepted. Lacrimal endoscopic micro-drilling and drainage, nasal endoscopic dacryocystorhinostomy have been carried out successively and are developing rapidly. But no matter which method is adopted, postoperative indwelling lacrimal duct ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F9/007A61F2/82A61F2/02A61F2/14
Inventor 吴文灿
Owner 吴文灿
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