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Image pick-up device for fluorescent molecule fault imaging device

A technology of fluorescent molecular tomography and imaging devices, which can be used in fluorescence/phosphorescence, diagnosis, application, etc., and can solve the problems of lack of cameras

Inactive Publication Date: 2009-03-11
TSINGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] One of the reasons for these problems is the lack of a camera that integrates multiple optical lenses in order to obtain more effective data

Method used

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  • Image pick-up device for fluorescent molecule fault imaging device

Examples

Experimental program
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Embodiment Construction

[0017] See figure 1 , the excitation light source 4 irradiates the experimental animal sample, the incident photons are transmitted in the experimental animal sample body and excite the fluorescent substance, and the fluorescence emitted by the fluorescent substance is transmitted in the experimental animal sample body and finally escapes the experimental animal sample body boundary, by The optical lens 3 images the fluorescent signal at the corresponding position on the boundary of the experimental animal sample on the branch end face of the composite optical fiber 2, and the fluorescent signal image is transmitted from each branch end of the composite optical fiber 2 to the composite end of the composite optical fiber 2 , the camera faces the composite end of the composite optical fiber 2 to obtain the fluorescent signal image, thereby obtaining the fluorescent signal image on the boundary of the experimental animal sample, wherein, 5 is a filter, located directly in front of...

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Abstract

The invention discloses an image pick-up device used for a fluorescence molecule faultage imaging device which belongs to the technical field of fluorescence molecule faultage imaging and is characterized by comprising a circular image pick-up ring; a vidicon internally embedded in the outer side of the vidicon, an excitation light source facing to the image pick-up ring and internally embedded in the inner side of the image pick-up ring; a plurality of optical lenses which are internally embedded in the inner side of the image pick-up ring are uniformly arranged in the same semi-ring of the image pick-up ring oppositely to the vidicon and align with the center of the ring together; compound optical fibers, the branch ends of which are inserted into the image pick-up ring from the outside and align with each optical lens; while one of the compound ends is connected with the ends of each branch end which are not inserted into the image pick-up ring; besides, the other ends of the compound ends are inserted into the vidicon from the outside and align with the vidicon. The image pick-up device used for a fluorescence molecule faultage imaging device has the advantages of obtaining more effective data, less imaging times and fast imaging speed.

Description

technical field [0001] The invention belongs to the technical field of fluorescence molecular tomography. Background technique [0002] Fluorescence molecular tomography (Fluorescence molecular tomography, also known as fluorescence molecular tomography) uses specific fluorescent molecular probes that have been widely used in biological and medical research to mark specific molecules or cells, and to analyze molecular levels in vivo. In vivo observation of the change of the target, and information such as the distribution of the target is provided through image reconstruction, which overcomes the limitations of planar imaging and obtains more information about biological and medical behaviors. It has the advantages of high sensitivity, quick and easy, low cost, and relatively high throughput. It supports in vivo research on related molecular events and meets the requirements of systematic observation of life processes in the 21st century. Rapid non-contact fluorescence mole...

Claims

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Application Information

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IPC IPC(8): A61B5/00G01N21/64
Inventor 白净金燕汪待发李明泽陈颀潇
Owner TSINGHUA UNIV