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Composition for preserving cadaver sample and preparation method thereof

A composition and specimen technology, applied in the field of anti-corrosion, preserved composition, and anti-mildew of corpses, can solve the problems of easy volatilization of anti-mildew liquid, expensive facilities, easy volatilization of ethanol, etc. The effect of easy availability of raw materials

Inactive Publication Date: 2009-07-08
WENZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are also obvious deficiencies in the actual application process: 1) formaldehyde has a strong pungent smell, and formaldehyde can cause damage to multiple organs and systems.
2) Seriously affect the teaching effect
3) Seriously pollute the air environment and water environment
At present, in order to improve the teaching environment, many units have adopted powerful exhaust equipment, which only transfers the pollution to the atmosphere; if the treatment of formaldehyde wastewater requires expensive facilities, some units even directly discharge the wastewater into the sewer
4) It is difficult to control the concentration of mildew
The anti-mildew liquid is volatile, and it will polymerize when exposed to air for a long time, and precipitate white paraformaldehyde or paraformaldehyde. In serious cases, the whole bottle of formalin will turn into a white paste, which will greatly reduce the fixing effect of the original liquid. , not even for fixed anticorrosion
5) For specimens preserved in formalin solution for a long time, the body is red in color and hard, and a layer of brown substance will adhere to the surface (especially places rich in hemoglobin, such as spleen, liver, bone, etc.), if it is not removed It will affect the effect of observing specimens, and it is also easy to cause misleading
Both of these two preservation solutions use ethanol as an effective antiseptic component, long-term use will cause the specimen protein to harden and deform, and because ethanol is volatile, it is difficult to control the effective concentration during use
At present, preservatives such as sodium benzoate and potassium sorbate are added to the corpse preservation solution, but the effect of inhibiting the mildew and decay of the corpse is not obvious

Method used

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  • Composition for preserving cadaver sample and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A composition for preserving cadaver specimens, which consists of sodium diacetate, dodecyltrimethylammonium chloride, potassium nitrate, sodium sulfate and ethylene glycol. Apply this composition, prepare 1000 liters of cadaver specimen preservation solutions, weigh each component by following weight:

[0021] Sodium diacetate: 1.0 kg

[0022] Dodecyltrimethylammonium chloride: 1.5 kg

[0023] Potassium nitrate: 10.0 kg

[0024] Sodium sulfate: 5.0 kg

[0025] Ethylene glycol: 15.0 kg

[0026] Add tap water to 1000 kg

[0027] The preparation process of the cadaver specimen preservation solution is as follows:

[0028] First add sodium diacetate with the above weight, ethylene glycol and dodecyltrimethylammonium chloride, stir evenly at room temperature and pressure, then add potassium nitrate and sodium sulfate, add tap water to 1000 liters, and stir for half an hour , the finished product after standing still.

Embodiment 2

[0030] A composition for preserving cadaver specimens, which consists of sodium diacetate, dodecyltrimethylammonium chloride, potassium nitrate, sodium sulfate and ethylene glycol. Apply this composition, prepare 1000 liters of cadaver specimen preservation solutions, weigh each component by following weight:

[0031] Potassium diacetate: 2.0 kg

[0032] Lauryltrimethylammonium chloride: 2.0 kg

[0033] Magnesium nitrate: 10.0 kg

[0034] Sodium sulfate: 5.0 kg

[0035] Dipropylene glycol: 15.0 kg

[0036] Add tap water to 1000 kg

[0037] The preparation process of the cadaver specimen preservation solution is as follows:

[0038] First add dipropylene glycol and dodecyltrimethylammonium chloride to the potassium diacetate of the above weight, stir evenly at normal temperature and pressure, then add magnesium nitrate and sodium sulfate, add to 1000 liters with tap water, stir for half an hour, After standing still, it is the finished product.

Embodiment 3

[0040] A composition for preserving cadaver specimens, which consists of sodium diacetate, dodecyltrimethylammonium chloride, potassium nitrate, sodium sulfate and ethylene glycol. Apply this composition, prepare 1000 liters of cadaver specimen preservation solutions, weigh each component by following weight:

[0041] Sodium diacetate: 1.0 kg

[0042] Dodecyltrimethylammonium chloride: 2 kg

[0043] Potassium nitrate: 10.0 kg

[0044] Zinc sulfate: 5.0 kg

[0045] Glycerol: 18.0 kg

[0046] Add tap water to 1000 kg

[0047] The preparation process of the cadaver specimen preservation solution is as follows:

[0048] First add sodium diacetate with the above weight, glycerin and dodecyltrimethylammonium chloride, stir evenly at room temperature and pressure, then add potassium nitrate and zinc sulfate, add tap water to 1000 liters, and stir for half an hour , the finished product after standing still.

[0049] Instructions:

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PUM

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Abstract

The invention discloses a composition for preserving corpse samples, and relates to corrosion prevention, rot resistance and preservation of corpses in medical teaching and scientific work. The composition comprises rot-proof and mold-proof active component, infiltration modifier and wetting agent, wherein the rot-proof and mold-proof active component is diacetate; the infiltration modifier is one or a mixture of two or more than two of nitrate, sulfate or hydrochloride according to any proportion; and the wetting agent is polylol. The invention also provides a method for preparing the composition for preserving the corpse samples. The method is special for preserving the corpse samples after setting treatment; the composition contains sodium diacetate, is used for preserving animal or human corpses, and can effectively solve the problems of corrosion prevention, rot resistance and preservation of the corpses; and the preservation liquid has the characteristics of long rot resistance time, good effect, no formaldehyde, safety and non-toxicity, easily obtained raw materials, and low price.

Description

technical field [0001] The invention relates to a composition for anti-mold, anti-corrosion and preservation of corpses in medical teaching and scientific research and a preparation method thereof. technical background [0002] For a long time, anatomy laboratories in medical colleges have been using formalin solution as the soaking solution for wet preservation of corpse specimens, and its main component is formaldehyde. Formaldehyde solution has the advantages of strong fixation and hardening effect on tissues, good permeability, low price, and good bactericidal and antiseptic effects. However, there are also obvious deficiencies in the actual application process: 1) formaldehyde has a strong pungent smell, and formaldehyde can cause damage to multiple organs and systems. . Formaldehyde seriously endangers the health of people exposed to it. 2) Seriously affect the teaching effect. The irritating smell of formaldehyde can irritate the mucous membrane of the respiratory...

Claims

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Application Information

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IPC IPC(8): A01N1/00
Inventor 周茹刘佳明周铁丽吴海峰郑特翁吉月吴新华曹建明
Owner WENZHOU MEDICAL UNIV
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