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Curable compositions and biofilm-resistant coatings therefrom

A composition and polymer technology, which is applied to hard substrates to provide substrates with anti-biofilm coatings, which can solve the problems of difficult control and treatment of biofilms, recurrence of biofilm growth, etc.

Inactive Publication Date: 2011-08-03
3M INNOVATIVE PROPERTIES CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although growth of planktonic cells can be controlled by antimicrobial or sterilizing treatments, biofilms themselves can be difficult to control and actually provide a reservoir of cells, which can lead to post-treatment colonization, infection and / or biofilm growth recurrence of

Method used

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  • Curable compositions and biofilm-resistant coatings therefrom
  • Curable compositions and biofilm-resistant coatings therefrom
  • Curable compositions and biofilm-resistant coatings therefrom

Examples

Experimental program
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example

[0098]All solvents and reagents were purchased from Aldrich Chemical Company, Milwaukee, WI, unless otherwise noted. All percentages and amounts are by weight unless otherwise indicated.

[0099] aggregation method

[0100] A copolymer of alkyl methacrylate and -polyethylene glycol monomethacrylate monomethyl ether (PEG1000, MW = about 1000) was prepared by the method described below and the specific components of the reaction mixture are listed in Table 1 listed in . Different mixtures of toluene, heptane, and ethanol were used to bring polyethylene glycol monomethacrylate methyl ether and alkyl methacrylate monomers into solution. In addition to monomers, the polymerization mixture also includes 5-10% methacryloxypropyltriethoxysilane / trimethoxysilane and 0.5-1% mercaptopropyltrimethoxysilane. VAZO 64 was used as polymerization initiator at a concentration of 0.5-1% (based on monomer weight). The monomers are dissolved in a solvent or solvent mixture. If the monomers ...

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PUM

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Abstract

The present invention provides a curable composition for use in retarding the formation of biofilms. The curable composition comprises a polymer derived from ethylenically unsaturated units having pendent long-chain aliphatic groups; ethylenically unsaturated units having pendent poly(oxyalkylene) groups; and ethylenically unsaturated units having pendent substrate-reactive groups; and a crosslinking agent.

Description

Background technique [0001] Biofilms are aggregates of microorganisms embedded within a highly hydrated matrix of extracellular polymers (usually polysaccharides) and other macromolecules. Biofilms can contain single or multiple microbial species and readily attach to various substrates such as medical devices (including catheters), soil, pipes, teeth, mucous membranes, and heat exchangers. In some environments, colonizing microorganisms are capable of growing in both biofilm (sessile) and free-living (planktonic) forms, and the cells associated with the biofilm can be in a ratio of 1000-10,000:1 Exceeds planktonic cells of the same species in number. Although growth of planktonic cells can be controlled by antimicrobial or sterilizing treatments, biofilms themselves can be difficult to control and actually provide a reservoir of cells, which can lead to post-treatment colonization, infection and / or biofilm growth recurrence. [0002] Preventing microbial colonization and e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08F8/00C08K5/00C08F220/18C09D133/04C09D171/02C09D5/16
CPCC09D133/04C08K5/548C08K5/57C09D5/1668C09D133/08C08K5/5425Y10T428/31699Y10T428/31928Y10T428/31663Y10T428/31913Y10T428/31616Y10T428/31565Y10T428/31649Y10T428/31935Y10T428/31576Y10T428/31681Y10T428/31797Y10T428/31612Y10T428/31667C08L2666/02
Inventor 阿方萨斯·V·博西尔斯杰里米·M·亚伍德鲁道夫·J·达姆斯约翰·J·小斯特夫科
Owner 3M INNOVATIVE PROPERTIES CO