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Medicinal dripping pill for treating hypertension

A technology of high blood pressure and medicine, which is applied in the field of drug dripping pills for the treatment of high blood pressure, can solve the problems of restricting clinical application, high blood pressure control can not meet people's wishes, etc., achieve remarkable therapeutic effect, no side effects, improve solubility and The effect of dissolution rate

Active Publication Date: 2011-06-29
BEIJING WBL PEKING UNIV BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effects of antihypertensive drugs on metabolism and target organ damage are still controversial, and most of them have certain side effects, which partially limit their clinical application.
Make the control of high blood pressure unsatisfactory

Method used

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  • Medicinal dripping pill for treating hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Red yeast rice 3kg Uncaria 5kg Dendrobium 3kg

[0034] The above-mentioned medicines were prepared into dry water extract pastes according to the conventional technology, and mixed to obtain the composition intermediate; according to the weight ratio, the composition intermediate: PEG 4000 =1:3.0 adding PEG 4000 , The preparation method of the dripping pill is: heating and melting the polyethylene glycol, adding the composition intermediate, mixing uniformly, keeping the temperature at 75±2℃; using a dripping pill machine to drip into the coolant, where the temperature of the coolant is 20± At 2°C, take out the drop pill after molding, remove the coolant on the surface, and pack it.

Embodiment 2

[0036] Red yeast rice 2kg Uncaria 7kg Dendrobium 4kg

[0037] The above-mentioned drugs were prepared into dry alcohol extract pastes according to the conventional process, and mixed to obtain the composition intermediate; according to the weight ratio, the composition intermediate: PEG 6000 =1:3.5 adding PEG 6000 , The preparation method of the dripping pill is: heating and melting the polyethylene glycol, adding the composition intermediate, mixing uniformly, keeping the temperature at 75±2℃; using a dripping pill machine to drip into the coolant, where the temperature of the coolant is 20± At 2°C, take out the drop pill after molding, remove the coolant on the surface, and pack it.

Embodiment 3

[0039] Red yeast rice 4kg Uncaria 4kg Dendrobium 2kg

[0040] The above-mentioned drugs are jointly extracted according to the conventional process to prepare a dry paste of water-extracted alcohol-precipitated macroporous resin adsorption column extract, and mixed to obtain a composition intermediate; according to the weight ratio, the composition intermediate: PEG 4000 =1:2.5 add PEG 4000 , The preparation method of the dripping pill is: heating and melting the polyethylene glycol, adding the composition intermediate, mixing uniformly, keeping the temperature at 75±2℃; using a dripping pill machine to drip into the coolant, where the temperature of the coolant is 20± At 2°C, take out the drop pill after molding, remove the coolant on the surface, and pack it.

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PUM

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Abstract

The invention discloses a medicinal dripping pill for treating hypertension, which consists of composition intermediates of red infested rice, uncaria, dendrobium and polyethylene glycol. The intermediates of the dripping pill are prepared from dry paste of extract of bulk drug prepared by the prior method. The medicinal dripping pill has remarkable treatment effect and no side effects.

Description

Technical field [0001] The invention relates to a medicine dropping pill, in particular to a medicine dropping pill for treating hypertension. Background technique [0002] Hypertension is a systemic disease caused by the interaction of polygenetic inheritance, environment, and multiple risk factors. It is a common and frequently-occurring disease worldwide. It is currently one of the main causes of death from human cardiovascular and cerebrovascular diseases. The worldwide incidence rate is as high as 10-20%, which is a major disease endangering human health. my country is a country with a high incidence of essential hypertension. According to the standard census of primary hypertension in 1991, the prevalence rate of hypertension over 15 years old in my country was 13.58%. According to this incidence, there are about 200 million people with hypertension in my country. If diagnosed according to existing standards, there will be more patients with hypertension. However, there...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61K9/20A61K47/34A61P9/12A61K47/10
Inventor 段震文郭树仁
Owner BEIJING WBL PEKING UNIV BIOTECH