Traditional Chinese medicine and western medicine composition containing fine powder and preparation method thereof

A technology for fine powder, traditional Chinese and western medicine, applied in the field of Chinese and western medicine composition containing fine powder and its preparation field, can solve problems such as increased operation difficulty, loss of effective components, loss of water-soluble components, etc., and achieves reduction of production cost and improvement of absorbency , the effect of increasing the surface area

Inactive Publication Date: 2010-01-06
GUANGZHOU BAIYUSN HUTCHISON WHAMPOA CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] This process has the following defects: (1) Acanthopanax uses 75% ethanol to reflux for 12 hours, which is labor-intensive and time-consuming, causing fat-soluble components to be easily destroyed, water-soluble components to be lost in large quantities, and active ingredients to be seriously lost
Since the original process cannot completely extract the water-soluble active components, the product has low curative effect; (2) The feeding process of expensive and fine medicinal materials is unreasonable
Deer antler is a kind of precious and fine medicinal material. The prescribing preparation is usually made into powder for expensive and fine medicine. The original process uses dilute ethanol to make 10% medicinal liquid and feeds it. It must be freshly prepared and should not be stored. This method increases the mass production of the workshop. Difficulty in operation, resulting in unnecessary cumbersome

Method used

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  • Traditional Chinese medicine and western medicine composition containing fine powder and preparation method thereof
  • Traditional Chinese medicine and western medicine composition containing fine powder and preparation method thereof
  • Traditional Chinese medicine and western medicine composition containing fine powder and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0010] Example 1 Preparation of Acanthopanax Radix Extract:

[0011] (1) Pilot test of the original process: get Acanthopanax 56kg, add 75% ethanol for continuous reflux extraction for 12 hours, filter, the filtrate reclaims ethanol, concentrates, and obtains liquid extract 1.58kg (moisture content 18%), yield It is 2.82%, and the content of isoferidin is 1.45mg / g (calculated as dry paste), and the liquid extract yield is lower than 4% (40g extract / 1000g medicinal material=4%) required by Pharmacopoeia. If the amount of extract is fed according to the Pharmacopoeia, it is necessary to increase the amount of Acanthopanax senticosus by 43.6%, and the cost increases.

[0012] (2) Trial production in the former craft workshop: get Acanthopanax 970kg, add 7 times the amount of 75% ethanol and extract continuously for 12 hours, filter, the filtrate reclaims ethanol, and the supernatant is filtered and concentrated to obtain liquid extract 21.7g (containing Moisture 17%), the yield ...

Embodiment 2

[0015] a. The preparation process of Qiangli Naoqingsu Tablets (original process)

[0016] 157g of Acanthopanax extractum (in theory, 3.93kg of Acanthopanax senticosus should be taken), 50ml of liquid extract of Schisandra chinensis, 28ml of antler extract, 35g of sodium glycerophosphate, and appropriate amount of auxiliary materials were made into 1000 tablets.

[0017] (1) First, 5.61kg of Acanthopanax medicinal material (actually more than 42.9% of the theoretical dosage just meets the requirements of the pharmacopoeia for extracting drug feeding), refluxed with 75% ethanol for 12 hours, filtered and concentrated to obtain 157g of Acanthopanax extract for later use ;

[0018] (2) Schisandra chinensis is made into liquid extract for subsequent use;

[0019] (3) 100g of velvet antler coarse powder, reflux with dilute ethanol to make 1000ml of 10% velvet antler essence for later use; weigh the above (1), (2), and (3) according to the prescription amount, mix with 35g of sodiu...

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Abstract

The invention discloses a traditional Chinese medicine and western medicine composition containing fine powder which is improved on the basis of the existing drug Qiangli Naoqingsu tablets and comprises the following effective components: siberian ginseng extract, Chinese magnoliavine fruit fluid extract, pantotrichum micropowder and sodium glycerophosphate; wherein, the pantotrichum micropowder is 10-300mu m of powder. The invention also discloses a preparation method of the traditional Chinese medicine and western medicine composition. The invention has the advantage that siberian ginseng component can be fully extracted which contains both fat-soluble component and water-soluble component; meanwhile, by adopting micronization technology, the surface area and the absorption of the drug can be increased and the damage on the effective component of pantotrichum is reduced in extraction process, thus improving the curative effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a Chinese and Western medicine composition containing fine powder and a preparation method thereof. Background technique [0002] At present, Qiangli Naoqingsu, also known as Gengniankang, is one of the famous and high-quality Chinese patent medicines. Clinically, it is mainly used for invigorating the kidney and spleen, nourishing the heart and calming the nerves, palpitations, insomnia, loss of appetite, mental fatigue and fatigue caused by deficiency of the spleen and kidney, and lack of nourishment of the mind and spirit. It has a certain therapeutic effect on menopausal syndrome. The technology of this variety originated in the early 1980s. Due to historical reasons, its production technology is not very reasonable. Its original preparation technology is: (1) Acanthopanax uses 7 times 75% ethanol, continuously refluxes for 12 hours, filters, and recovers...

Claims

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Application Information

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IPC IPC(8): A61K36/79A61K9/28A61K9/48A61P25/20A61P1/14A61P15/12A61K35/32A61K31/047
Inventor 覃仁安李楚源黄竹英罗佩霞蔡越冬李淑如
Owner GUANGZHOU BAIYUSN HUTCHISON WHAMPOA CHINESE MEDICINE
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