A traditional Chinese medicine composition for treating essential hypertension

A technology of essential hypertension and composition, which is applied in the direction of drug combination, cardiovascular system diseases, and pharmaceutical formulations, can solve the problems of ineffective curative effect and obvious side effects of drugs, and achieve the effect of improving microcirculation

Inactive Publication Date: 2012-02-15
孙蓉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the clinical treatment of hypertension is mainly based on the principles of life rules, reasonable diet, and physical exercise, supplemented by drug therapy. The drug therapy of hypertension is mainly based on diuretics, vasodilators, calcium channel blockers, adrenergic Receptor blockers, sympathetic nerve inhibitors and other Western medicines and related traditional Chinese medicines are the main treatments, but the clinical efficacy of the medicines currently used to treat essential hypertension is often not obvious, and most of the medicines have obvious side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Take Uncaria 1300g, add 6 times the amount of 75% ethanol, reflux extraction 2 times, each time for 1 hour, filter, combine the filtrate, reclaim the ethanol under reduced pressure, and set aside;

[0021] (2) Add 300g Cyperus cyperi with 6 times the amount of water, soak for 3 hours, extract the volatile oil by steam distillation, and collect the distilled aqueous solution in another device for later use; use 6 times the amount of β-cyclodextrin for the volatile oil, and clathrate at 30°C for 1 hour ;

[0022] (3) Medicinal dregs, Scrophulariaceae 520g, Radix Astragali 630g, add 8 times the amount of 75% ethanol for reflux extraction twice, each time for 1 hour, filter, combine filtrate, recover ethanol under reduced pressure, and set aside; after alcohol extraction, medicinal dregs add 6 Double the amount of water to decoct twice, 1 hour each time, filter, and combine the filtrates.

[0023] (4) Combine the above-mentioned distilled aqueous solution and each alco...

Embodiment 2

[0026] (1) Get Uncaria 1350g, add 6 times the amount of 75% ethanol, reflux extraction 2 times, each time for 1 hour, filter, combine the filtrate, reclaim the ethanol under reduced pressure, and set aside;

[0027] (2) Add 8 times the amount of water to Cyperus cyperi, soak for 2 hours, extract the volatile oil by steam distillation, and collect the distilled aqueous solution in another device for later use; use 6 times the amount of β-cyclodextrin for the volatile oil, and clathrate at 40°C for 1 hour ;

[0028] (3) Medicinal dregs, Scrophulariaceae 540g, Radix Astragali 650g, add 8 times the amount of 75% ethanol to reflux extraction twice, each time for 1 hour, filter, combine filtrates, recover ethanol under reduced pressure, and set aside; after alcohol extraction, medicinal dregs add 8 Double the amount of water to decoct twice, 1 hour each time, filter, and combine the filtrates.

[0029] (4) Combine the above-mentioned distilled aqueous solution and each alcohol extr...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating essential hypertension, which uses Chinese medicine Uncaria scrophulariae, Scrophulariae scrophulariae, Radix Astragali and Rhizoma Cyperi as raw materials, and is extracted with ethanol to make pharmaceutically acceptable tablets, granules, etc. dosage form. The medicine of the present invention has the effect of clearing the liver and replenishing qi, and is mainly used for the treatment of essential hypertension with symptoms of irritability, insomnia, dizziness, fatigue, fatigue, bitter mouth and rapid pulse. The TCM syndrome is liver-fire deficiency. Drug efficacy tests show that it has the effect of significantly lowering blood pressure and has no toxic or side effects.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition for treating essential hypertension, in particular to a Chinese patent medicine prepared from Chinese herbal medicines, and also relates to a preparation method of the medicine. Background technique: [0002] Hypertension is one of the most common cardiovascular diseases. It is closely related to coronary heart disease and cerebrovascular disease. The incidence of coronary heart disease in hypertensive patients is significantly higher than that of non-hypertensive people. According to the survey, 62.9% of patients with coronary heart disease -93.6% had hypertension. The national death toll due to cardiovascular and cerebrovascular diseases has accounted for 34% of the total death toll. Among untreated hypertensive patients, 70-80% died of stroke, and 11%-15% died of coronary heart disease. 5%-10% die from renal failure. Therefore hypertension is hailed as the "silent killer" of hum...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61P9/12
Inventor 孙蓉吕丽丽衣银萍张作平于晓尹建伟
Owner 孙蓉
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