Method for fully-automatic on-line sampling of freeze dryer

Abstract

The invention relates to a method for fully-automatic on-line sampling of a freeze dryer. The method comprises that: in a freeze-drying box with a vacuum state, a motor drives an outer driving turnplate through a coupling; the outer driving turnplate adopts a magnetic coupling method to be connected with and drive an inner driving turnplate; the inner driving turnplate drives a manipulator on a crank through the coupling to grab a sample bottle placed on a board layer; the crank drives the manipulator to convey the sample bottle into an opened inner wicket of a vacuum chamber, the inner wicket is closed, an outer wicket is opened, the manipulator loosens, and the sample bottle drops off; and an operator takes off the sample bottle from one side of the outer wicket, and then the outer wicket closes automatically. The method overcomes the defect of a method that a long rod extends into the freeze-drying box to clamp a bottle manually for taking the bottle out of the middle vacuum chamber, realizes that sampling is performed in a vacuum state, and prevents polluted air from entering during the sampling or leakage caused by aging due to alternating low temperature and steam high temperature from impacting the quality of freeze-drying products in the freeze-drying box and discarding the products in bulk as useless; and the freeze-drying pass rate reaches over 99 percent.

Description

1. Technical field [0001] The invention relates to a fully automatic online sampling method for a freeze dryer, and relates to a method for fully automatic sampling of products in a vacuum state on the freeze dryer. 2. Background technology [0002] Vacuum freeze dryer, commonly known as freeze dryer, is a drying equipment widely used in medicine and food industries. to achieve the purpose of drying and dehydrating the material. At present, with the further integration of my country's pharmaceutical and food industries with international standards, the requirements for the use of freeze dryers in vaccines, blood products, biopharmaceuticals, medicines, health care products, etc. are getting higher and higher. Because all substances are sublimated in a vacuum state, the whole process is carried out in a sealed freeze-drying box, and the operator cannot directly understand the real state and condition of the freeze-dried product before the end of the entire freeze-drying proc...

AI Technical Summary

Problems solved by technology

The obvious effect after the implementation of this technology is: overcoming the method of using a long rod to extend into the freeze-drying box, manually clamping a bottle through the intermediate vacuum chamber and then taking it out, and realizing sampling in a vacuum state, thus effectively avoiding the During sampling, polluted air enters or leaks due to alternating low temperature and steam high temperature aging, which affects the quality of internal freeze-dried products, causing the entire batch of products to be scrapped and defective.

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