Culture medium for in vitro culture of epidermal melanophore
A technology of melanocytes and in vitro culture, applied in artificial cell constructs, animal cells, vertebrate cells, etc.
Active Publication Date: 2010-06-16
许爱娥 +1
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The effect of metaproterenol on epidermal melanocyte growth and melanin synthesis has not been reported yet
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Abstract
The invention provides a culture medium for in vitro culture of epidermal melanophore. In the culture medium, a basic culture medium which is suitable for in vitro culture of the epidermal melanophore is used as a substrate, and growth factors (1), cAMP accelerant (2) and serum (3) are added into the substrate. The invention has the beneficial effects that the invention provides the culture medium which is specially used for in vitro culture of the epidermal melanophore, and the culture medium can be used for culturing epidermal melanophore with strong propagation capacity, migration capacityand melanin synthesizing capacity, can enable melanophore of patients to better grow and differentiate in vitro, and can be used for transplantation treatment of depigmented or nonpigmented dermopathic patients.
Description
(1) Technical field The invention relates to a medium for culturing epidermal melanocytes in vitro. (2) Background technology Skin color is primarily determined by the combination of pigments manufactured by the skin and natural pigments contained in the top layers of the skin. The epidermis on the surface of the epithelial layer of the skin contains epidermal melanocytes that produce skin pigment (melanin). In people with hypopigmented or amelanotic skin conditions, the melanocytes in the skin are missing, damaged, or nonfunctional, resulting in white spots on various parts of the body. Melanin is not only protective, it is also crucial for skin aesthetics. Some diseases can cause local melanocyte destruction, loss or inhibition of cell function, affecting the skin pigment production system, resulting in skin hypopigmentation or loss of pigmentation. Such abnormalities can cause serious psychological and sociological damage to the patient. Vitiligo is a special skin p...
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IPC IPC(8): C12N5/071
Inventor 许爱娥胡诞宁傅丽芳周妙妮尉晓冬洪为松关翠萍
Owner 许爱娥
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