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Application of traditional Chinese medicine composition in preparation of medicines for treating silicosis

The technology of a composition and traditional Chinese medicine is applied in the application field of preparing medicine for treating silicosis, and can solve the problems of undisclosed pharmaceutical composition application and the like

Active Publication Date: 2010-06-30
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent does not disclose the application of the pharmaceutical composition in the preparation of medicines for the treatment of silicosis

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicines for treating silicosis
  • Application of traditional Chinese medicine composition in preparation of medicines for treating silicosis
  • Application of traditional Chinese medicine composition in preparation of medicines for treating silicosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] prescription:

[0036] Ginseng 89g Ophiopogon japonicus 112g Cornus officinalis 224g Salvia miltiorrhiza 224g

[0037] Fried Suanzaoren 186g, Sangjisheng 186g, Radix Paeoniae Rubra 89g, Ground Beetle 75g

[0038] Gansong 89g Coptidis 45g Southern Schisandra 67g Keel 149g

[0039] Preparation:

[0040] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0041] b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extracts are combined, filtered, and set aside;

[0042] c) in the above-mentioned prescription, the ground beetle is pulverized into fine powder, and is set aside;

[0043] d) In the above prescr...

Embodiment 2

[0047] prescription:

[0048] Ginseng 45g Ophiopogon japonicus 112g Cornus officinalis 224g Salvia miltiorrhiza 225g Fried jujube seed 186g

[0049] Sangjisheng 186g Radix Paeoniae Rubra 89g Gansong 45g Wood Beetle 35g Coptidis 45g

[0050] Southern schisandra 67g, keel 149g.

[0051] Preparation:

[0052] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0053]b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extracts are combined, filtered, and set aside;

[0054] c) in the above-mentioned prescription, the ground beetle is pulverized into fine powder, and is set aside;

[0055] d) In the above prescript...

Embodiment 3

[0059] prescription:

[0060] Ginseng 175g Ophiopogon japonicus 192g Cornus officinalis 421g Salvia miltiorrhiza 440g Fried jujube seed 395g

[0061] Sangjisheng 396g Radix Paeoniae Rubra 188g Ground Beetle 98g Gansong 188g Coptidis 85g

[0062] Southern schisandra 147g, keel 278g.

[0063] Preparation:

[0064] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0065] b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extracts are combined, filtered, and set aside;

[0066] c) in the above-mentioned prescription, the ground beetle is pulverized into fine powder, and is set aside;

[0067] d) In the above pr...

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Abstract

The invention provides an application of a traditional Chinese medicine composition in the preparation of medicines for treating silicosis. The medicine composition comprises 12 types of traditional Chinese herbs of ginseng, radix ophiopogonis, dogwood and the like. Clinical tests prove that the medicine composition used for treating the silicosis can obviously ameliorate clinical symptoms and the lung function and has favorable curative effect.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating silicosis. It belongs to the technical field of Chinese herbal medicine preparations. Background technique [0002] Silicosis is the most serious type of pneumoconiosis, due to long-term inhalation of free silicon dioxide (Si0 2 ) caused by dust. There is extensive nodular fibrosis in the lungs, which affects lung function and loses working ability in severe cases. [0003] Generally speaking, dust containing more than 80% of free silica often causes typical diffuse collagen fiber changes in the lungs, with rapid progression and fusion prone to occur. When the free silica is less than 80%, the lesions are less typical and the disease progression is slower. When it is less than 10%, it mainly causes interstitial fiber changes, develops more slowly, and is classified as other pneumoconiosis. [0004] A large amount of d...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K9/00A61K9/14A61K9/16A61K9/20A61K9/48A61P11/00A61K35/02A61K35/64
Inventor 宋剑李向军郑立发安军永王超李云鹏
Owner HEBEI YILING MEDICINE INST
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