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Traditional Chinese medicine composition and preparation for treating diarrhea and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition, preparation and preparation for treating diarrhea, can solve the problems of easy breeding of microorganisms, large dosage, slow onset of effect, etc., and achieve good curative effect and high bioavailability , use comfortable effect

Active Publication Date: 2012-07-25
HENGKANG MEDICAL GROUP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional Chinese medicine compositions disclosed above are all directly used as medicines, which have a slow onset of action, are prone to breed microorganisms, have high cost, and take large doses.

Method used

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  • Traditional Chinese medicine composition and preparation for treating diarrhea and preparation method thereof
  • Traditional Chinese medicine composition and preparation for treating diarrhea and preparation method thereof
  • Traditional Chinese medicine composition and preparation for treating diarrhea and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 The preparation method screening of Chinese medicine composition of the present invention

[0033] In this example, by designing the following four routes, the optimal method for preparing the traditional Chinese medicine composition is screened out.

[0034] Route 1: 200g of pepper, 100g of tangerine peel, 100g of Evodia rutaecarpa, 200g of amomum, add 10 times the amount of water, decoct twice, 1 hour each time, filter, concentrate the filtrate to collect the ointment, dry under reduced pressure at 60-70°C, and crush into The fine powder is the dry extract.

[0035] Route 2: Add 200g of pepper, 100g of tangerine peel, 100g of Evodia rutaecarpa, 200g of amomum, add 10 times the amount of water, extract the volatile oil for 4 hours, filter, add 8 times the amount of water to the dregs, decoct twice, 1 hour each time, filter, The filtrate and the extracted volatile oil filtrate are combined and concentrated to collect the extract, dried under reduced pressur...

Embodiment 2

[0059] Example 2 The preparation method optimization of Chinese medicine composition of the present invention

[0060] 1) Alcohol precipitation process optimization of water extracts of tangerine peel, evodia and amomum

[0061]The traditional Chinese medicine compositions prepared according to the routes 1-4 in the above-mentioned Example 1 were preliminarily made into cataplasms, and the formation of the cataplasms was observed (results are shown in Table 4A).

[0062] Table 4A makes the molding result of cataplasm

[0063]

[0064] It can be seen from Table 4A that there are many impurity components in the medicinal solution extracted by adding water to tangerine peel, evodia, and amomum. According to the route 3 screened out in Example 1, the cataplasm ointment is prepared directly by using the water extract, and the cohesive strength of the ointment is weak , poor skin adhesion, can not meet the requirements of external preparations. Therefore, it is investigated w...

Embodiment 3-10

[0116] Following examples 3-10 are the preparation method embodiment of Chinese medicine composition of the present invention

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Abstract

The invention provides a traditional Chinese medicine composition and a preparation for treating diarrhea and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 1 part of dried orange peel, 1 part of fructus evodiae, 2 parts of fructus amomi and 2 parts of pepper, wherein a water extraction method is adopted to extract the dried orange peel, the fructus evodiae and the fructus amomi to obtain volatile oil and a water extraction and alcohol precipitation extractive, and an organic solvent extraction method isadopted to extract the pepper to obtain an organic solvent extractive. The traditional Chinese medicine composition can be made into a clinically acceptable oral preparation or external preparation including cataplasm, a granule, a capsule or a tablet. The traditional Chinese medicine composition prepared by adopting the preparation method has high content of active components, better curative effect and simple preparation method. The prepared preparation saves medicines and has high bioavailability and tiny toxic and side effects. In particular, the invention provides a safe, effective and convenient preparation for treating infantile diarrhea.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating diarrhea and a preparation method thereof, as well as a preparation containing the traditional Chinese medicine composition and a preparation method thereof, which are used for treating diarrhea, and are especially suitable for treating infantile diarrhea. Background technique [0002] Infantile diarrhea is a common and frequently-occurring disease in pediatrics. In addition to affecting the absorption of nutrients in food by infants, it also consumes nutrients stored in the body and damages certain body tissues. Long-term chronic diarrhea will make children thin and weak, reduce their resistance, and be prone to various diseases. This not only affects the normal growth and development of infants, but also causes complications. Because of its harmfulness to children's health, WHO lists diarrhea control as a global strategy. There are problems such as children's difficulty...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61P1/12
Inventor 张康宁洛勇杨婷廖立东邓艳
Owner HENGKANG MEDICAL GROUP CO LTD