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Medicinal composition for treating infant asthma and preparation method and use thereof

A composition and technology for infants and young children, applied in the directions of drug combination, pharmaceutical formula, drug delivery, etc., to achieve the effects of prolonging the incubation period, relieving asthma symptoms, and reducing the number of animals

Inactive Publication Date: 2010-10-13
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no Chinese patent medicine specifically for children with asthma on the market

Method used

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  • Medicinal composition for treating infant asthma and preparation method and use thereof
  • Medicinal composition for treating infant asthma and preparation method and use thereof
  • Medicinal composition for treating infant asthma and preparation method and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The preparation of embodiment 1 medicament oral liquid of the present invention

[0026] [prescription]

[0027] Ephedra 75g, Chuanshegan 83.5g, Asarum 16.5g, Tinglizi 75g, Scutellaria baicalensis 83.5g, Coltsfoot flower 83.5g, Aster 83.5g, make 1000ml

[0028] [preparation method]

[0029] The above seven flavors, asarum, add water, distill and extract, collect aromatic water, and set aside; Aster add 80% ethanol, reflux extraction, filtrate recover ethanol for use; the above five flavors such as Asarum, aster herb residue and the rest of ephedra, add water to decoct three times, filter , combine the filtrate and the above-mentioned distillation mother liquor, concentrate under reduced pressure, add ethanol, leave standstill, filter, reclaim the ethanol from the filtrate, add the above-mentioned aromatic water, sorbic acid, polysorbate 80 (wherein, the consumption of sorbic acid is 0.1% of the total amount of oral liquid) %, the dosage of polysorbate 80 is 2.0% of th...

Embodiment 2

[0036] The preparation of embodiment 2 pharmaceutical capsules of the present invention

[0037] Take ephedra 52.5g, shegan 58.45g, asarum 11.55g, Tinglizi 52.5g, scutellaria baicalensis 58.45g, coltsfoot flower 58.45g, aster 58.45g. According to the method of Example 1, prepare the filtrate to recover ethanol, add double distilled liquid, mix, add starch to granulate, granulate, and prepare granules.

Embodiment 3

[0038] The preparation of embodiment 3 pharmaceutical granules of the present invention

[0039] Take Ephedra 97.5g, Shegan 108.55g, Asarum 21.45g, Tinglizi 97.5g, Scutellaria baicalensis 108.55g, Coltsfoot flower 108.55g, Aster 108.55g;

[0040] or

[0041] Ephedra 217g, Shegan 347g, Asarum 130g, Tinglizi 347g, Dilong 347g, Scutellaria baicalensis 347g, Bellflower 173g, Citrus aurantii 173g, Aster 260g, Coltsfoot 260g, according to the method of Example 1, prepare the filtrate to recover ethanol, add heavy Distillate, mix, add starch to granulate, granulate, compress into tablets to obtain tablets.

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Abstract

The invention provides a medicinal composition for treating infant asthma, which is a preparation prepared from the following raw materials in part by weight: 52.5 to 97.5 parts of ephedra herb, 58.45 to 108.55 parts of rhizoma belamcandae, 11.55 to 21.45 parts of manchurian wildginger, 52.5 to 97.5 parts of pepperweed seed, 58.45 to 108.55 parts of radix scutellariae, 58.45 to 108.55 parts of common coltsfoot flower, and 58.45 to 108.55 parts of tatarian aster root. The invention also provides a preparation method and use of the medicinal composition. The medicinal composition has the effects of relieving exterior syndrome and promoting expectoration, removing phlegm and curing asthma, mainly treats young child cough, sputum obstruction on throat, asthmatic and breath holding symptom, and the like, and is applied to infant asthma, capillary bronchitis, asthma, and the like. The medicinal composition for treating the infant asthma has the advantages of clinical revealing rate of 73.3 percent, clinical total effective rate of 96.6 percent, and obvious improvement on relieving asthma symptoms after treatment.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating infantile asthma, which belongs to the field of medicines. Background technique [0002] Bronchial asthma is a common, refractory chronic lung disease. Over the past ten years, the morbidity and mortality in some countries such as Britain, the United States, and Australia have all increased, and the incidence rate in my country is close to 1% (1992 years), and the incidence rate is high under the age of 12. The age of onset is less than 6 years old, and about 84.8% of patients are less than 3 years old. The incidence rate of children's asthma in Sichuan Province is 1.95%, ranking second in the country. The preliminary conclusion of the second national survey in 2001 has a great increase in the incidence rate of asthma. Recent studies have shown that allergic inflammation of the airway (AAI) and airway hyperresponsiveness (AHR) play a dominant role in the pathogenesis of asthma. In rece...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/00A61K9/16A61K9/20A61K9/48A61P11/06A61P11/00A61P11/14
Inventor 刘小凡
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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