Uncaria sustained-release capsule preparation and preparation method thereof

Abstract

The invention discloses an uncaria slow release capsule preparation and a preparation method thereof. The preparation is prepared from 1 to 15 parts by weight of uncarine or uncaria rhomotoxine and 73.2 to 130.2 parts by weight of accessories, wherein the accessories comprise 65 to 85 parts of excipient, 3 to 15 parts of coating agent, 5 to 20 parts of wetting agent, 0.1 to 0.5 part of surface active agent, 0 to 9 parts of plasticizer and 0.1 to 0.7 part of sunscreen. Compared with the prior art, by a slow release technology of the invention, medicaments are slowly released; the fluctuation of the concentration of plasma medicaments is effectively reduced; a peak valley phenomenon caused by frequent administration of an ordinary preparation is avoided; the utilization rate of the medicaments is enhanced; the medical cost is reduced; and the direct stimulation of the medicaments for the gastrointestinal tract is reduced. Therefore, side effects are reduced; patients are easy to endure the medicaments; and the preparation is beneficial to long-term treatment and hypertensive treatment. In addition, the invention also simplifies the technology; the preparation process of a capsule is easier to operate and more convenient to carry and take; the problem of the prior art is solved; and the purpose of the invention is achieved.

Description

technical field

[0001] The invention relates to an Uncaria sustained-release capsule preparation and a preparation method thereof, belonging to the technical field of medicines. Background technique

[0002] Hypertension belongs to the pain syndromes of dizziness, headache, liver yang and liver wind in traditional Chinese medicine. The main symptoms of the patient are dizziness, headache and elevated blood pressure. It can be caused by the imbalance of liver and kidney yin and yang due to heredity or long-term mental stress, depression, or addiction to fat, sweet, and excessive drinking. In severe cases, symptoms such as stroke and coma may occur. Hypertension is a common disease and the most important risk factor for major diseases such as coronary heart disease and cerebrovascular disease that lead to human death. The morbidity and mortality of cardiovascular and cerebrovascular diseases are closely related to the blood pressure level of patients. Therefore, all countrie...

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