Anti-gout composition, preparation method and application thereof in preparation of anti-gout drugs

A composition and anti-gout technology, applied in the directions of drug combination, active ingredients of hydroxyl compounds, pharmaceutical formulations, etc., can solve the problem of small selectivity of doctors, and achieve the effect of good anti-gout treatment effect.

Active Publication Date: 2010-10-27
JIANGSU KANGYUAN SUNSHINE PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

All other types of drugs have their limitations or adverse reactions, so doctors have little choice in clinical medication

Method used

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  • Anti-gout composition, preparation method and application thereof in preparation of anti-gout drugs
  • Anti-gout composition, preparation method and application thereof in preparation of anti-gout drugs
  • Anti-gout composition, preparation method and application thereof in preparation of anti-gout drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] Embodiment 1, an anti-gout composition, is characterized in that the weight ratio of raw materials of the composition is as follows: Lijiang Arrowhead: 180; Rhubarb: 150; Speranthema: 120; Borneol 5; made into 1000ml. Among them, the rhubarb is crushed into coarse particles, and the medicinal material is wetted with an appropriate amount of 80% ethanol to fully swell the medicinal material. For about 1 hour, the percolation barrel is added, and an appropriate amount of 80% ethanol is added, soaked for 24 hours, and the percolation solution is collected. 800ml; Lijiang Arrowhead Mushroom and Speranthum spp. were refluxed twice with 8 times the amount of 70% ethanol for 1.5 hours each time. The extracts were combined, the ethanol was recovered, and concentrated to an extract with a relative density of 1.10-1.15 (50°C). Slowly add the rhubarb percolate into the extract, stir while adding, mix evenly, place, centrifuge (10000-15000r / m), and set aside. Grind borneol finely, ...

Embodiment 2

[0246] Embodiment 2 is basically the same as Embodiment 1, but there are the following changes: the weight ratio composition of the raw material medicine is: Arrowhead mushroom 180; Rhubarb 150;

Embodiment 3

[0247] Embodiment 3 is basically the same as Embodiment 1, but has the following changes: the weight ratio composition of the raw material medicine is: Arrowhead mushroom 160; Rheum 120;

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Abstract

The invention relates to an anti-gout composition, a preparation method and an application thereof in the preparation of anti-gout drugs, and the composition comprises the following pharmaceutical raw materials by weight ratio: 160-220 parts of Indian iphigenia bulb, 120-180 parts of rhubarb or Chinese paris rhizome, 100-150 parts of garden balsam stem and 3-8 parts of borneol or menthol. The optimized weight ratio is as follows: 180 parts of Lijiang Indian iphigenia bulb, 150 parts of rhubarb or Chinese paris rhizome, 120 parts of garden balsam stem and 5 parts of borneol or menthol. The pharmaceutical raw materials are prepared into 1000ml or 1000g. The further optimization is that the pharmaceutical raw materials comprise the rhubarb or the Chinese paris rhizome, extracts of the Lijiang Indian iphigenia bulb and the garden balsam stem and solution of the borneol or the menthol. The invention further provides the preparation method of the anti-gout composition and the application of the anti-gout composition in the preparation of the anti-gout drugs. The invention provides the effective anti-gout traditional Chinese medicine composition for making up for the deficiency that the prior art is lack of the anti-gout drugs prepared by traditional Chinese medicine. The anti-gout composition can obtain better anti-gout treatment effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to an anti-gout composition, a preparation method of the anti-gout composition, and an application of the anti-gout composition in preparing anti-gout medicine. Background technique [0002] Gout was once generally considered to be a disease of the rich, but later it was found to be a common disease all over the world. Whether in European and American countries or in the oriental nation, the prevalence of gout has a tendency to increase year by year. Statistics in recent years show that the prevalence of gout in all age groups is 0.84%. At present, there are 8-12 million gout patients in my country. Hyperuricemia is the main biochemical basis of gout, and its incidence is higher, and the age of onset tends to be younger. 1.4% to 5.7% of people over 20 years old have high blood uric acid levels, and the peak incidence is 40 to 50 years old . 5% to 12% of hyperuricemia will eventual...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P19/06A61K31/045A61K31/125
Inventor 殷书梅王宓徐超林新艳夏月李吉峰
Owner JIANGSU KANGYUAN SUNSHINE PHARMA CO LTD
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