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Preparation process of medicinal composition compounded from astragaloside and astragalus polyose

A technology of astragaloside IV and astragalus polysaccharide is applied in the directions of drug combinations, medical preparations containing active ingredients, pharmaceutical formulations, etc. The effect of color gradient changes, high resource utilization, and reduction of decolorization steps

Active Publication Date: 2012-05-30
广州泽力医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] A large number of literature studies have shown that due to different origins, processing methods, and harvesting seasons, the types and contents of chemical components in Astragalus medicinal materials are not completely consistent. Increase the difference, so that the content of the chemical components of the corresponding preparations is unstable between batches

Method used

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  • Preparation process of medicinal composition compounded from astragaloside and astragalus polyose
  • Preparation process of medicinal composition compounded from astragaloside and astragalus polyose

Examples

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Embodiment 1

[0043] Raw material: Astragalus medicinal material 70kg.

[0044] Main equipment: medicine cutting machine, pulverizer, differential pressure extractor, inorganic membrane filter, nanofiltration concentrator, reverse osmosis concentrator, thin film evaporation concentrator, vacuum dryer.

[0045] Preparation process:

[0046] 1. Pretreatment of medicinal materials: After washing the medicinal materials of Astragalus membranaceus, cut them into 2-3mm grains by a medicine cutter, and crush them into 20-mesh coarse powder.

[0047] 2. Extraction: Take 1000 kg of purified water at room temperature and mix them evenly with Astragalus membranaceus coarse powder, and extract through continuous pressure difference.

[0048] 3. Microfiltration: Collect the extract and filter it through a 500nm inorganic ceramic membrane for clarification.

[0049] 4. Concentration: The clarified liquid from microfiltration is concentrated to a solid content of 16.6% through a 100-200KDa nanofiltratio...

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Abstract

The invention discloses a preparation process of a medicinal composition compounded from astragaloside and astragalus polyose. The invention mainly relates to the preparation process of the medicinal composition compounded from the astragaloside and the astragalus polyose, in particular to a preparation process of a medicinal particularly injection standard composition, which adopts the combination of differential pressure type extraction, multi-stage membrane separation and concentration and column separation and refining, prepares high-purity astragaloside and neutral astragalus polyose at the same time by using the same batch of raw materials, and compounds the astragaloside and the astragalus polyose according to certain proportion.

Description

technical field [0001] The present invention mainly relates to a preparation process of a medicinal composition derived from Astragalus membranaceus, especially a combination of pressure difference extraction combined with multi-stage membrane separation and concentration, and column separation and refinement. A preparation process of a standard composition for medicinal use, especially for injection, which is quantitatively compounded with pure astragaloside IV and neutral astragalus polysaccharide in a certain proportion. Background technique [0002] Astragalus is the dried root of Astragalus membranaceus (Fisch.) Bge.var.monghalicus (Bge.) Hsiao or Astrgalus membranaceus (Fisch.) Bge. of leguminous plant. Tool invigorating qi and solidifying the surface, diuretic detoxification, evacuation of pus, astringing sores and promoting granulation. It is used to treat qi deficiency and fatigue, lack of appetite, loose stools, subsidence of middle qi, prolonged diarrhea and prol...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K31/7048A61P37/02
Inventor 刘乡乡宋力飞
Owner 广州泽力医药科技有限公司
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