Depressurization chewing gum and preparation method thereof
A technology of chewing gum and formula, which is applied in the field of chewing gum, can solve the problems of a single tooth cleaning function, and achieve the effects of enhancing compliance, improving medication compliance, and reducing blood pressure and blood lipids
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example 1
[0031] (1) Preparation of eucommia ethanol extract
[0032] Eucommia bark peeled x After chopping, use a concentration of 60% ethanol a Solution, according to the ratio of mass to volume 1:10 (unit is g / ml), mix well; 70 ℃ b Heating and extracting for 1 hour, the filter residue was re-used with 60% ethanol with a ratio of mass to volume of 1:8 (unit is g / ml) a Reflux extraction 2 times c , each time 1h d , the extracts were combined, concentrated under reduced pressure to obtain an alcohol extractant, and dried to obtain an alcohol extract. We also changed the conditions marked by letters x, a, b, c, and d, and measured by ultraviolet spectrophotometry, there was no significant difference in the content of antihypertensive active ingredients in each group.
[0033] x
a
b
c
d
Ethanol concentration (%)
Reflux extraction times
Extraction time (h)
Eucommia bark
50
...
example 2
[0048] (1) Preparation of eucommia lignans
[0049] According to the method of Example 1, the concentrated solution of Eucommia ethanol extract under reduced pressure was first prepared; the concentrated solution was first eluted with water and then 50% ethanol through the adsorption column, and the 50% ethanol washed part was collected, concentrated, and slowly added to 4 times In water, filter, concentrate the filtrate, and freeze-dry to obtain eucommia lignans. We use pinoresinol diglucoside, a monomer substance of chlorogenic acids in eucommia lignans, as a standard, and determine the lignan content to be 71%.
[0050] (2) Preparation of Antihypertensive Chewing Gum
[0051] Purchase 2.2kg of degradable gum base and 0.2kg of maltitol and heat them at 50°C for 24h respectively. Put the heated gum base and maltitol into the mixer and mix thoroughly, add 3kg eucommia lignan, 4.8kg xylitol, 0.6kg isomaltose, 0.2kg citric acid, 0.2kg lemon fruit flavor and 0.1kg Aspartame and...
example 3
[0060] (1) Preparation of Compound Eucommia Aqueous Extract
[0061] Take 4690g of Eucommia ulmoides, 4690g of Motherwort, 2810g of Prunella vulgaris, 2810g of Scutellaria baicalensis, 1310g of Uncaria vulgaris, and the above five flavors, add water and decoct three times, 1 hour each time, combine the decoction, filter, let stand for 24 hours, absorb the supernatant, and concentrate to relative density 1.35 ~ 1.38, the temperature is the extract at 80°C.
[0062] (2) Preparation of Antihypertensive Chewing Gum
[0063] 4kg of compound eucommia extract was crushed into 80 meshes, then 0.1kg of aspartame, 0.9kg of fructose and fruit flavor, 4kg of xylitol were crushed into 100 meshes, mixed evenly, and 1kg of maltitol was made into 70% maltitol Aqueous solution, the mixture of compound eucommia powder, fruit flavor and xylitol is added to maltitol aqueous solution, mixed, granulated with 16 mesh, granulated with 20 mesh, dried below 80°C, and then compressed into tablets.
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