thiogalactosittderivatives, preparation method and application thereof
A technology of galactopyranoside and thiolation, which is applied in the direction of sugar derivatives, metabolic diseases, drug combinations, etc., and can solve problems such as liver toxicity and weight
Inactive Publication Date: 2011-01-26
TIANJIN INSTITUTE OF PHARMA RESEARCH
View PDF1 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
These drugs have good therapeutic effects, but there are safety problems in long-term treatment, such as: liver toxicity and weight gain, etc.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
Embodiment 2-10
Embodiment 11
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention relates to the field of medicaments relevant to diabetes mellitus, in particular to 2-type sodium glucose transporter (SGLT2) inhibitors containing athiogalactosiTt structure, a preparation method of the inhibitors, a medicinal composition containing the inhibitors and application of the inhibitors to preparing a medicament for treating the diabetes mellitus, wherein the definition of a group is described as the specification.
Description
technical field The invention relates to the field of medicine related to diabetes. Specifically, the present invention relates to a sodium glucose transporter type 2 (SGLT2) inhibitor containing a thiogalactose structure, which has a therapeutic effect on diabetes, a preparation method thereof, and a pharmaceutical composition containing them. Background technique There are currently about 170 million diabetics in the world, and the vast majority of them are type II (ie, non-insulin-dependent) diabetics. The antidiabetic drugs currently in clinical use mainly include metformin, sulfonylureas and insulin drugs. In recent years, thiazolidinedione drugs, α-glucosidase inhibitors and dipeptidyl peptidase-IV have also been listed on the market. Inhibitors etc. These drugs have good therapeutic effects, but there are safety problems in long-term treatment, such as liver toxicity and weight gain. Sodium glucose transporter type 2 (SGLT2) is a new target for the treatment of di...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More IPC IPC(8): C07H17/00A61K31/7056A61P43/00A61P3/10
Inventor 赵桂龙刘巍王玉丽高云龙王致峰徐为人汤立达邹美香张士俊谭初兵刘冰妮
Owner TIANJIN INSTITUTE OF PHARMA RESEARCH
Features
- R&D
- Intellectual Property
- Life Sciences
- Materials
- Tech Scout
Why Patsnap Eureka
- Unparalleled Data Quality
- Higher Quality Content
- 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com