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Vesicle and cosmetic containing the same

A technology for vesicles and lotions, which is applied in the field of improving stability, can solve the problems that the stability of heat-resistant film does not have practicality, etc., and achieve the effects of excellent moisturizing effect, usability and high safety.

Inactive Publication Date: 2011-03-23
SHISEIDO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this component does not have sufficient practicality in terms of its characteristics, heat resistance, film stability over time, cost, etc.

Method used

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  • Vesicle and cosmetic containing the same
  • Vesicle and cosmetic containing the same
  • Vesicle and cosmetic containing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The stability of the vesicles obtained according to the formulation and production method shown in Table 1 below was evaluated. The evaluation method of stability is as follows.

[0045] Determination of Turbidity Change

[0046] For each test sample immediately after the preparation of the vesicles, and after storage at 0°C, RT (room temperature), and 50°C for one month, use an absorption photometer (Ubest-55 JASCO Corporation) to measure the concentration at a wavelength of 600 nm. Absorbance (Abs.) represents the change in turbidity as (Abs. after storage / Abs. immediately after preparation). The results are shown in Table 2.

[0047] Exterior

[0048] The dispersion state of the vesicles of each test sample after preparation was visually observed for 1 hour, and evaluated according to the following criteria. The results are shown in Table 2.

[0049] ◯: Agglomerates and precipitates were not observed.

[0050] Δ: Some aggregates and precipitates were found....

Embodiment 2

[0065] Cosmetics (lotions) were prepared according to the formulations and production methods shown in Table 3 below, and the stability of vesicles in each sample was measured. The evaluation method is as follows.

[0066] Determination of Turbidity Change

[0067] For each sample immediately after preparation, and after storage at -5°C, 0°C, RT (room temperature), and 37°C for one month, use an absorption photometer (Ubest-55 JASCO Corporation) to measure The absorbance (Abs.) of the product is expressed as (Abs. after storage / Abs. immediately after preparation) to express the change in turbidity. The results are shown in Table 4.

[0068] In addition, the samples of Test Examples 11 and 12 were similarly calculated for changes in turbidity when they were stored for 2 months under the conditions of -5°C, 0°C, RT (room temperature), and 37°C. The results are shown in Table 5.

[0069] [table 3]

[0070]

[0071] (Manufacturing method)

[0072] Dissolve sucrose diest...

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Abstract

Provided is a vesicle comprising a sucrose fatty acid diester and 5 to 30 wt.%, with respect to the diester, of an acylmethyl taurine salt. The vesicle is characterized by having the sucrose fatty acid diester as a main membrane component, and has excellent dispersion stability. Further provided are a cosmetic containing the vesicle, and a toner made by dispersing the vesicle in a solvent such as alcohol.

Description

[0001] This application claims the priority of Japanese Patent Application No. 2008-101721 for which it applied on April 9, 2008, and takes in the content here. technical field [0002] The present invention relates to the improvement of the stability of vesicles, especially in cosmetics. Background technique [0003] The technology of microencapsulating active ingredients such as pharmaceuticals for use in and out of living organisms, due to the advantages of inhibiting the metabolism of capsule inclusions and maintaining the efficacy of drugs for a long time, it is not only in the fields of medicine and food, but also in the field of cosmetics. Explore practicality. [0004] As a microencapsulation technology in the field of cosmetics, the application of liposomes and vesicles (enclosed small cells including lipid bimolecular membranes) using phospholipids such as lecithin as a membrane component is known. However, this component does not have sufficient practicality in t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/14A61K8/46A61K8/60A61K9/127A61K47/20A61K47/26A61Q19/00
CPCA61K8/466A61K8/60A61K8/14A61Q19/00A61P17/16
Inventor 高桥明子冈本亨
Owner SHISEIDO CO LTD