Medicinal composition for treating children with tic disorders and preparation method thereof

A composition and obstacle technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as restrictions and difficult cures

Inactive Publication Date: 2012-05-23
李冰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disease has a slow course, and the symptoms are good and bad, and they often appear alternately. After treatment, the symptoms can be improved in most cases, but it is difficult to cure.
The current treatment plan is mostly oral administration of haloperidol (haloperon), with an effective rate of 70% to 85%, usually starting from a small dose, 0.25 to 2 mg / d, divided into 2 to 3 times, and generally a total of 1.5 to 2 mg per day , but the drug often has side effects such as drowsiness, fatigue, dizziness, constipation, tachycardia, dysuria and extrapyramidal side effects, which limit the clinical use

Method used

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  • Medicinal composition for treating children with tic disorders and preparation method thereof
  • Medicinal composition for treating children with tic disorders and preparation method thereof
  • Medicinal composition for treating children with tic disorders and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1, the weight ratio of raw materials: 10 parts of Rehmannia glutinosa, 6 parts of Cornus officinalis, 3 parts of pinellia, 6 parts of Zhuru, 3 parts of Citrus aurantium, 6 parts of Chinese yam, 6 parts of tangerine peel, 6 parts of Alisma, 6 parts of Moutan bark 9 parts of Poria cocos, 3 parts of roasted licorice, 15 parts of keel, 15 parts of oyster, 6 parts of earthworm, 5 parts of silkworm, 6 parts of Uncaria, 6 parts of cicada slough, 3 parts of Shichangpu, and 10 parts of mother-of-pearl.

Embodiment 2

[0037] Example 2, the weight ratio of raw materials: 20 parts of Rehmannia glutinosa, 10 parts of Cornus officinalis, 6 parts of pinellia, 10 parts of Zhuru, 6 parts of Citrus aurantii, 10 parts of Chinese yam, 10 parts of tangerine peel, 10 parts of Alisma, 10 parts of Moutan bark 12 parts of poria cocos, 6 parts of licorice, 20 parts of keel, 20 parts of oyster, 12 parts of earthworm, 6 parts of silkworm, 10 parts of uncaria, 10 parts of cicada slough, 6 parts of calamus, and 20 parts of mother-of-pearl.

Embodiment 3

[0038] Example 3, the weight ratio of raw materials: 30 parts of Rehmannia glutinosa, 12 parts of Cornus officinalis, 10 parts of pinellia, 12 parts of Zhuru, 10 parts of Citrus aurantium, 12 parts of Chinese yam, 12 parts of tangerine peel, 12 parts of Alisma, 12 parts of Moutan bark 15 parts of poria cocos, 10 parts of licorice, 30 parts of keel, 30 parts of oyster, 15 parts of earthworm, 9 parts of silkworm, 12 parts of uncaria, 12 parts of cicada slough, 9 parts of calamus, and 25 parts of mother-of-pearl.

[0039] Chinese medicine of the present invention can be prepared by following method:

[0040] (1) The volatile oils are extracted from dried tangerine peel, tree peony cortex and citrus citrus citrus coarse powder by steam distillation respectively, and are collected and mixed for later use;

[0041] (2) Mix Rehmannia glutinosa, Cornus officinalis, Banxia, ​​Zhuru, Yam, Alisma, Poria cocos, Zhilicorice, keel, oyster, earthworm, silkworm, Uncaria, cicada slough, calamu...

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PUM

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Abstract

The invention discloses a medicinal composition for treating children with tic disorders and a preparation method thereof, aiming at solving the problem on treating the children with tic disorders. The medicinal composition is characterized by comprising the following raw medicinal materials in weight proportion: 10-30 parts of prepared rehmannia root, 6-12 parts of common macrocarpium fruit, 3-10 parts of pinellia tuber, 6-12 parts of bamboo shavings, 3-10 parts of fruit of immature citron, 6-12 parts of common yam rhizome, 6-12 parts of tangerine peel, 6-12 parts of oriental waterplantain rhizome, 6-12 parts of moutan bark, 9-15 parts of poria cocos, 3-10 parts of prepared licorice, 15-30 parts of drgon's bones, 15-30 parts of oyster, 6-15 parts of earthworm, 5-9 parts of stiff silkworm, 6-12 parts of uncaria, 6-12 parts of cicada slough, 3-9 parts of grassleaf sweelflag rhizome, and 10-25 parts of nacre. Clinical experiments prove that the medicinal composition has the characteristics of good curative effect and higher safety for treating the children with tic disorders and is worthy of clinical application and popularization.

Description

【Technical field】 [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating children's tic disorder and a preparation method thereof. 【Background technique】 [0002] The etiology of tic disorder in children is unknown, with a prevalence rate of 0.1% to 0.5%. It is manifested as sudden, repeated rapid, involuntary muscle movement tics and vocal tics in one or more parts of any part of the body. According to the composition and duration of movements, it can be divided into transient tic disorder, chronic motor tic or vocal tic disorder and Tourette syndrome, which may be accompanied by inattention, hyperactivity, learning difficulties, compulsive movements and thinking or other conduct disorder. This disease is a slow course of disease, and the symptoms are good and bad and often appear alternately. After treatment, the symptoms of most cases can be improved, but it is more difficult to cure. The cur...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P21/00A61P25/00A61K35/02A61K35/56A61K35/64A61K35/618A61K35/62
Inventor 李冰张瑞蕾颜萍
Owner 李冰
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