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Pepper extract with function of resisting infection of ureaplasma urealyticum and mycoplasma hominis

A technology of Mycoplasma hominis and Zanthoxylum bungeanum extract is applied in the directions of medical preparations containing active ingredients, antibacterial drugs, plant raw materials, etc., and can solve the problems of poor treatment effect and increased drug resistance.

Inactive Publication Date: 2011-05-18
黑龙江省中医研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention aims to solve the problem that the current resistance of Ureaplasma urealyticum and Mycoplasma hominis to antibiotics increases, resulting in poor therapeutic effect, and provides a Zanthoxylum bungeanum extract with anti-infection effects of Ureaplasma urealyticum and Mycoplasma hominis

Method used

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  • Pepper extract with function of resisting infection of ureaplasma urealyticum and mycoplasma hominis
  • Pepper extract with function of resisting infection of ureaplasma urealyticum and mycoplasma hominis
  • Pepper extract with function of resisting infection of ureaplasma urealyticum and mycoplasma hominis

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specific Embodiment approach 1

[0013] Specific embodiment one: The Zanthoxylum bungeanum extract that has anti-Ureaplasma urealyticum and Mycoplasma hominis infection effect of the present embodiment is extracted by the following method: Zanthoxylum bungeanum is pulverized into powder, charged with supercritical CO 2 In the extraction kettle, the extraction temperature is 30-55°C, the separation temperature is 25-45°C, the extraction pressure is 15-35MPa, the separation pressure is 4-6MPa, CO 2 The flow rate is 4-12 L / h, and the extraction time is 1-2 hours, so as to obtain the Zanthoxylum bungeanum extract.

[0014] The Zanthoxylum bungeanum extract described in this embodiment can be made into oral (pills, granules, oral liquid, tablet, capsule or soft capsule) and external (lavage, gel) with pharmaceutically acceptable carriers or excipients. elixirs, suppositories, sprays or effervescents) or sterile injections. The acceptable carriers are: cocoa soybean oil, semi-synthetic glycerin fatty acid esters, ...

specific Embodiment approach 2

[0016] Embodiment 2: This embodiment differs from Embodiment 1 in that the extraction temperature is 35-50°C. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0017] Embodiment 3: The difference between this embodiment and Embodiment 1 is that the extraction temperature is 40-45°C. Others are the same as in the first embodiment.

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Abstract

The invention provides a pepper extract with a function of resisting infection of ureaplasma urealyticum and mycoplasma hominis, relating to a pepper extract and aiming at solving the problems that the drug resistance of the ureaplasma urealyticum and the mycoplasma hominis to antibiotic is increased to cause poor treatment effect. The pepper extract is obtained by extraction through the following method: pepper is ground into powder, the powder is put into a supercritical CO2 extraction kettle, the extraction temperature is 30-55 DEG C, the separating temperature is 25-45 DEG C, the extraction pressure is 15-35MPa, the separation pressure is 4-6MPa, the flow of CO2 is 4-12, and the extraction time is 1-2 hours, and then the pepper extract is obtained. The pepper extract is non-toxic, has the functions of resisting the infection of ureaplasma urealyticum and mycoplasma hominis and resisting the infection of drug-resistant ureaplasma urealyticum and drug-resistant mycoplasma hominis, and is applied in the field of resisting the infection of mycoplasma.

Description

technical field [0001] The invention relates to a Zanthoxylum bungeanum extract. Background technique [0002] Urogenital tract infections caused by Ureaplasma urealyticum and Mycoplasma hominis have the highest incidence among sexually transmitted diseases, and can not only cause a wide range of non-gonococcal reproductive tract infections, such as bartholinitis, colitis, cervicitis, etc. It can also cause upper reproductive tract infections such as endometritis, salpingitis, oophoritis, and pelvic inflammatory disease, leading to adverse consequences such as infertility, infertility, fetal intrauterine infection, and miscarriage. Men may be complicated by prostatitis, epididymitis, women's cervix and salpingitis. Because mycoplasma lacks a cell wall, the antibiotic treatment that interferes with cell wall synthesis, such as penicillin and β-lactam drugs, is basically ineffective; mycoplasma is sensitive to antibiotics that affect cell protein synthesis, such as tetracycli...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P31/04
Inventor 王伟明潘五九
Owner 黑龙江省中医研究院
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