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Traditional Chinese medicine composition for treating colpitis mycotica and preparation method of traditional Chinese medicine composition

A technology of fungal vaginitis and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of fungal vaginitis, and can solve problems such as easy dependence and drug resistance, great harm to pregnant women, and unsatisfactory effects. Achieve good social value and economic benefits, less toxic and side effects, and strong anti-inflammatory and insect-removing effects

Inactive Publication Date: 2011-08-10
南通市星期七旅游开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The technical problem to be solved by the present invention is that the western medicines for this disease have antibacterial drugs such as fluconazole tablets, indomethacin tablets, furosemide tablets, metronidazole, ciprofloxacin, etc., microecological treatment preparations such as lactobacillus, Bacillus licheniformis; however, the effects of antibiotics on various genitourinary system inflammations and dysmenorrhea in gynecology are far from satisfactory. Treating this type of gynecological diseases with western medicines not only has poor curative effect and easy recurrence, but also has large side effects, and is easy to produce dependence and dysmenorrhea. Drug resistance, and quite harmful to pregnant women, but there is no specific Chinese patent medicine

Method used

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  • Traditional Chinese medicine composition for treating colpitis mycotica and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating colpitis mycotica and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating colpitis mycotica and preparation method of traditional Chinese medicine composition

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0063] The preparation method of honey refining pill of the present invention is: get mulberry parasite 1000g, angelica 1000g, atractylodes macrocephala 1000g, motherwort 1000g, astragalus 1000g, jujube 1000g, dodder 1000g, privet fruit 1000g, mulberry 1000g, anemarrhena 1000g, raspberry 1000g, Schisandra 1000g, Scutellaria baicalensis 1000g, Patrinia 1000g; firstly crush the raw materials for oral administration into coarse powder, then further pulverize, pass through a 100 mesh to 120 mesh sieve, so that the amount of fine powder that can pass through the sieve reaches 30%, collect and pass through Sieve the fine powder to obtain fine powder a; then put the coarse powder that cannot pass through the 120-mesh sieve into a multi-functional extraction tank for extraction twice, add 10 times the amount of water to decoct for 1 hour for the first time, and add 8 times the amount of water to decoct for the second time Boil for 1 hour, combine the two decoctions, filter to obtain th...

experiment example 2

[0087] Experimental example 2: long-term toxicity test data

[0088] 1. Experimental method

[0089] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean the depilatory agent, observe each group of guinea pigs after 24 hours to be coated with respectively 0.2,0.4 and 0.8ml of the present invention's orally administered traditional Chinese medicine preparation Honey Refined Pills, contain crude drug 92,184 and 368mg respectively, another group is coated with vehicle 0.8ml twice a day, For 30 consecutive days, the general condition of the guinea pigs was observed. After the experiment, the animals were sacrificed for hematology, blood biochemical and pathological examinations.

[0090] 2. Results

[0091] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of ​​g...

experiment example 3

[0092] Experimental example 3: Cumulative toxicity test:

[0093] Chinese medicine preparation oral administration capsule of the present invention is to mice by 7.69,19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine preparation of the present invention The hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of the rats were not significantly affected. After 3 weeks of drug withdrawal, there was no significant change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.

[0094] Pharmacodynamic test

[0095] Test purpose: adopt whole animal tes...

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Abstract

The invention provides a traditional Chinese medicine composition for treating colpitis mycotica, wherein the oral medicines are: 10-20 parts of viscum album, 10-20 parts of angelica, 10-20 of bighead atractylodes rhizome, 10-20 parts of motherwort, 10-20 of astragalus root, 10-20 parts of fructus zizyphi sativae, 10-20 parts of semen cuscutae, 10-20 parts of fruit of glossy privet, 10-20 of mulberry, 10-20 parts of rhizoma anemarrhenae, 10-20 of fructus rubi, 10-20 parts of Chinese magnoliavine fruit, 10-20 parts of scutellaria baicalensis, and 10-20 parts of patrinia; the external medicines are: 10-30 parts of root of Chinese pulsatilla, 10-30 parts of golden cypress, 10-30 parts of radix sophorae flavescentis, 10-30 parts of fructus cnidii, 10-30 parts of cortex dictamni, 10-30 parts of folium artemisiae argyi, 10-30 parts of clove, 10-30 parts of Chinese prickly ash, 10-30 parts of smoked plum, 10-30 parts of rhizoma smilacis glabrae, 10-30 parts of borneol, 10-30 parts of herba, and 10-30 parts of mint. The composition has fast effects of relieving itching, killing insect and degerming, strongly diminishes inflammation antibiotic property, and is high in bacteriostasis ratio, convenient for administration, easy for manufacturing and low in cost.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating fungal vaginitis and a preparation method thereof. Background technique [0002] Fungal vaginitis, as the name suggests, is caused by fungal infection. Its sickness rate is already higher than trichomonal vaginitis. Medically, fungal infection is also called candida infection, so fungal vaginitis is also called candidal vaginitis, which is more common in young girls, pregnant women, diabetic patients, and postmenopausal patients who have been treated with large doses of estrogen. Patients with fungal vaginitis manifest as increased leucorrhea, itching and burning sensation in the vulva and vagina, painful urination, redness and edema around the vulva, and various changes in the epidermis; shallow blisters and papules may occur; eczema-like erosions may also form ; indiv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K36/90A61K9/02A61K9/48A61P15/02A61K31/045
Inventor 梁轶聪李佃场王漪
Owner 南通市星期七旅游开发有限公司
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