Traditional Chinese medicine composition for treating colpitis mycotica and preparation method of traditional Chinese medicine composition
A technology of fungal vaginitis and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of fungal vaginitis, and can solve problems such as easy dependence and drug resistance, great harm to pregnant women, and unsatisfactory effects. Achieve good social value and economic benefits, less toxic and side effects, and strong anti-inflammatory and insect-removing effects
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preparation example Construction
[0063] The preparation method of honey refining pill of the present invention is: get mulberry parasite 1000g, angelica 1000g, atractylodes macrocephala 1000g, motherwort 1000g, astragalus 1000g, jujube 1000g, dodder 1000g, privet fruit 1000g, mulberry 1000g, anemarrhena 1000g, raspberry 1000g, Schisandra 1000g, Scutellaria baicalensis 1000g, Patrinia 1000g; firstly crush the raw materials for oral administration into coarse powder, then further pulverize, pass through a 100 mesh to 120 mesh sieve, so that the amount of fine powder that can pass through the sieve reaches 30%, collect and pass through Sieve the fine powder to obtain fine powder a; then put the coarse powder that cannot pass through the 120-mesh sieve into a multi-functional extraction tank for extraction twice, add 10 times the amount of water to decoct for 1 hour for the first time, and add 8 times the amount of water to decoct for the second time Boil for 1 hour, combine the two decoctions, filter to obtain th...
experiment example 2
[0087] Experimental example 2: long-term toxicity test data
[0088] 1. Experimental method
[0089] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean the depilatory agent, observe each group of guinea pigs after 24 hours to be coated with respectively 0.2,0.4 and 0.8ml of the present invention's orally administered traditional Chinese medicine preparation Honey Refined Pills, contain crude drug 92,184 and 368mg respectively, another group is coated with vehicle 0.8ml twice a day, For 30 consecutive days, the general condition of the guinea pigs was observed. After the experiment, the animals were sacrificed for hematology, blood biochemical and pathological examinations.
[0090] 2. Results
[0091] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of g...
experiment example 3
[0092] Experimental example 3: Cumulative toxicity test:
[0093] Chinese medicine preparation oral administration capsule of the present invention is to mice by 7.69,19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine preparation of the present invention The hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of the rats were not significantly affected. After 3 weeks of drug withdrawal, there was no significant change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.
[0094] Pharmacodynamic test
[0095] Test purpose: adopt whole animal tes...
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