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Pest-control compositions and methods having high target and low non-target activity

A technology for controlling pests and compositions, applied in the directions of botanical equipment and methods, animal repellents, plant growth regulators, etc.

Inactive Publication Date: 2011-08-10
TYRATECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This can be particularly troublesome for insects, as their large populations and short generation times can lead to rapid development of resistance to specific insecticides

Method used

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  • Pest-control compositions and methods having high target and low non-target activity
  • Pest-control compositions and methods having high target and low non-target activity
  • Pest-control compositions and methods having high target and low non-target activity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0163] Compositions for controlling insects were prepared according to the following table:

[0164] Element

CAS

W / W

white thyme oil

8007-46-3

20.6

Isopropyl myristate

110-27-0

34.3

[0165] oil of wintergreen

45.1

[0166] Compositions were tested against fleas by adding various concentrations of the composition to a collagen membrane (1 gallon per 1000 square feet) and then placing fleas (n=3, replicas of 5 fleas each) on the membrane ability to control insects. 跳蚤死亡率在附 figure 2 Measured at the time points indicated in .

[0167]The compositions were then tested by adding various concentrations of the compositions to the collagen membrane (1 gallon per 1000 square feet) and then placing fleas (n=3, 5 tick replicas each) on the membrane Insect control against ticks. Tick ​​mortality in the image 3 Measured at the time points indicated in .

[0168] The data reflect the selectivity of the ...

Embodiment 2

[0170] LD of chemicals that will be tested 50 Values ​​(determined for wild-type flies) apply locally to wild-type and tyramine receptor mutant (TyrRneo30) lines. Mortality was determined 24 hours after treatment. Data are the average of three replicates with 5 flies per replicate. This experiment was repeated five times.

[0171] data (attached Figure 4 ) shows the selectivity of the thymol and carvacrol test chemicals, which do not affect flies expressing mutant forms of the tyramine receptor.

Embodiment 3

[0173] Test compositions for controlling parasites were prepared according to Table 1.

[0174] Mice were treated with various dose levels of the test composition for different periods of time (see appendix Figure 5 ). Briefly, the test composition was administered to mice in varying amounts (1 mg / kg body weight, 10 mg / kg body weight, or 100 mg / kg body weight) over a period of three or three weeks, after which 200 hatchable eggs of H. nana Infect every animal. During the incubation period of 2 weeks post-infection, the animals continued to be treated with the different test amounts of the blend composition. During the third week post-infection, the feces of the treated and infected mice were examined, and then the mice were sacrificed at the end of the third week to determine the cure rate. Background infection numbers were established by infecting untreated animals with 200 hatchable eggs of H. nana.

[0175] The results obtained show that, although the composition is ef...

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Abstract

Embodiments of the invention relate to compositions and methods for selective pest control wherein the compositions include active agents that in combination have a first activity against a selected target pest and a second activity against a selected non-target organism and wherein the first activity is greater than the second. Further embodiments of the invention relate to a method for developing selective pest control compositions and low-resistance pest control compositions.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to US Provisional Patent Application No. 61 / 082,601, filed July 22, 2008, which is hereby incorporated by reference in its entirety. technical field [0003] The present invention generally relates to pesticidal methods and compositions that minimize the impact of non-target species while providing highly selective control of target pest species and reducing the likelihood of the target species developing resistance. Background technique [0004] Toxic effects of pesticides on target and non-target species can be exploited using LD 50 value to evaluate. LD 50 Represents the dose required to kill fifty percent of the population of test animals (eg, rats, fish, mice, cockroaches). LD 50 The lower the , the more effective the insecticide and the lower the amount required to kill the target pest; i.e., LD 50 The toxicity of a pesticide with a value of 10 mg / kg is LD 50 The value is 1...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N25/00
CPCA01N65/00A01N31/08A01N65/16A01N65/22A01N31/02A01N37/02A01N2300/00
Inventor 埃萨姆·埃南
Owner TYRATECH
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