Anselmella miltoni girault molecular detection primer, detection method and application thereof
A technology for Milton's honeybee and molecular detection, which is applied to biochemical equipment and methods, microbial determination/inspection, etc., can solve the problems of molecular detection and identification methods without Milton's jellyfish, and achieves the effect of convenient use.
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Embodiment 1
[0017] 1) Extraction of total DNA
[0018] Method 1: Extraction of total DNA from multiple insects
[0019] Genomic DNA was extracted using the Universal Genomic DNA Extraction Kit Ver 3.0 produced by TaKaRa, including the following steps:
[0020] (1) Put 30 insects into a mortar, add 500 μL of Solution A (provided by TaKaRa’s kit) and 1.0 μL of RNase A1 (provided by TaKaRa’s kit) for grinding, and collect the homogenate into Collection Tube (TaKaRa's kit provided);
[0021] (2) Rinse the mortar with 200 μL of Solution A and transfer to the Collection Tube, and incubate at 65 °C for 5-10 min;
[0022] (3) Add 400 μL of Solution B (provided by TaKaRa’s kit) to the Collection Tube, shake and mix; then add 1 mL of 4°C pre-cooled Solution C (provided by TaKaRa’s kit), and mix well , centrifuge at 12000 rpm for 2 min;
[0023] (4) Discard the upper organic phase, then add 1 mL of 4 ℃ pre-cooled Solution C, mix thoroughly, and centrifuge at 12,000 rpm for 2 min;
[0024] (5) D...
Embodiment 2
[0043] Specific detection of PCR method in Adenia milton
[0044] Take 30 A. milton, A. eucalyptus and A. eucalyptus, and extract total DNA respectively according to the method in Example 1, then carry out PCR amplification, and detect the results by agarose gel electrophoresis. Results A DNA fragment of 317 bp was detected in A. milton, but no DNA fragment of 317 bp was detected in A. eucalyptus and A. erythrina. Test results such as figure 1 shown. It shows that the established PCR method has good specificity and can be used for rapid detection of A. milton.
Embodiment 3
[0046] PCR detection of a single Adenia milton
[0047] Take a single Adenia milton, extract the total DNA according to the method in Example 1, then perform PCR amplification, and agarose gel electrophoresis to detect the results. Results A DNA fragment of 317 bp was detected in a single A. milton. Test results such as figure 2 shown. It shows that the established PCR method has good sensitivity and can be used for the rapid detection of a single A. milton.
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