Preparation method of konjac sponge medical dressing

A sponge and konjac technology, which is applied in the field of medicine, can solve the problems of inability to meet the requirements of medical dressings, slow water absorption rate, small water absorption ratio, etc., and achieve the effect of preventing collapse, fine and smooth surface, and no cracks on the surface.

Inactive Publication Date: 2014-04-16
WUHAN TEXTILE UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The methods for preparing the konjac sponge material reported in the literature at present are all freeze-thaw methods. The structure of this type of konjac sponge is compact, the water absorption multiple is small, and the water absorption rate is slow, and the product is hard when dry, and the surface is rough. When it is wet, it is easy to breed bacteria. Will degrade in a short time, difficult to store
Therefore, this type of konjac sponge can only be used to make products such as towels, face wipes and powder puffs, and cannot meet the requirements of medical dressings.

Method used

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Examples

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Effect test

preparation example Construction

[0022] A kind of preparation method of konjac sponge medical dressing, the preparation method of konjac sponge medical dressing comprises the steps:

[0023] A preparation of konjac powder aqueous solution

[0024]Mix distilled water and konjac powder according to the mass ratio of 1:0.01-0.05, then stir and dissolve at a high speed, the speed of the high-speed mixer is 5000-10000r / min, the dissolution temperature is 30-60°C, and the dissolution time is 2-6h. A homogeneously dissolved konjac powder aqueous solution is obtained, wherein the content of glucomannan in the konjac powder is 50%-90%, and the molecular weight is 100000-500000.

[0025] Because konjac fine powder has high molecular weight, high viscosity and low purity, and is difficult to dissolve, the present invention adopts high-speed stirring and high-temperature dissolution to realize the dissolution of konjac fine powder in distilled water and shorten the dissolution time.

[0026] b Forming of konjac sponge ...

Embodiment 1

[0037] Take by weighing 100 grams of distilled water, 5 grams of konjac powder with a glucomannan content of 50% and a molecular weight of 100,000, add the konjac powder to 60°C distilled water while stirring, stir and dissolve at a high speed, and use a high-speed mixer The rotating speed is 5000r / min, and the dissolving time is 6h to obtain a homogeneously dissolved konjac powder aqueous solution; the konjac powder aqueous solution is divided into molds, and the mold is placed in a refrigerator at -26°C for pre-freezing. The pre-freezing time is 5h, then be placed in the vacuum oven of 50 ℃ and carry out vacuum drying, and vacuum tightness is 60Pa, and drying time is 4h, then demoulding obtains the konjac sponge of forming; Take by successively the sodium hydroxide of 100 grams of ethanol, 5 grams, Add sodium hydroxide to ethanol and stir evenly to obtain a coagulation bath of konjac sponge. Soak the formed konjac sponge in the above coagulation bath for curing. The curing te...

Embodiment 2

[0039] Take by weighing 100 grams of distilled water and 1 gram of konjac powder with a glucomannan content of 90% and a molecular weight of 500,000 in turn, add the konjac powder to 30°C distilled water while stirring, stir and dissolve at a high speed, and use a high-speed mixer The rotation speed of the konjac powder is 10000r / min, and the dissolution time is 2h to obtain a homogeneously dissolved konjac powder aqueous solution; the konjac powder aqueous solution is divided into molds, and the mold is placed in a refrigerator at -16°C for pre-freezing. The pre-freezing time is 12h, then be placed in the vacuum oven of 30 ℃ and carry out vacuum drying, and vacuum tightness is 100Pa, and drying time is 12h, then demoulding obtains the konjac sponge of forming; Take by successively the sodium hydroxide of 100 grams of ethanol, 1 gram, Add sodium hydroxide to ethanol and stir evenly to obtain a coagulation bath of konjac sponge. Soak the formed konjac sponge in the above coagula...

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PUM

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Abstract

The invention discloses a Konjac sponge medical dressing and a preparation method thereof and belongs to the technical field of medicines. The preparation method comprises the following steps: making an aqueous solution of Konjac refined powder containing 50% to 90% of Konjac glucomannan and having a molecular weight of 100000 to 500000, forming Konjac sponge, curing the Konjac sponge, cutting the Konjac sponge, packaging, and sterilizing to obtain the Konjac sponge medical dressing with liquid absorption capacity of 100 to 300 g / g and air permeability of 80% to 90%. The Konjac sponge medical dressing has a smooth and crack-free surface; is excellent in flexibility, elasticity, air permeability, barrier property, wear resistance, water absorptivity, biocompatibility, degradability and removability; can be used for treating different types of skin wounds, such as surgical wounds and burn wounds; and achieves the effects of preventing bacterial infection, accelerating tissue repair and promoting wound healing.

Description

technical field [0001] The invention relates to a konjac sponge medical dressing and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] The skin has important functions such as resisting the invasion of pathogenic bacteria outside the body, excreting human waste, preventing the evaporation of water in the human body, regulating the temperature of the human body, and feeling the stimulation of pressure, cold and temperature. When the skin is damaged due to trauma, abrasions, burns, and ulcers, it is easy to be infected with bacteria, or fluid loss occurs and cause various complications. Therefore, medical dressings are required to protect the wound and promote wound healing during treatment. The traditional medical dressing (gauze) only plays the role of covering the wound surface. With the development of society and the advancement of science and technology, especially the rapid development of modern medicine, biology an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/40
Inventor 朱平张传杰方义徐雁翎王恒洲
Owner WUHAN TEXTILE UNIV
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