The invention relates to a hierarchical porous molecular sieve and a catalyst prepared from the molecular sieve, specifically to a preparation method of a hierarchical porous Beta molecular sieve andan Ni catalyst thereof, and solves the problems of single pore structure, low utilization rate, incomplete opening, only an adsorption role, easy sintering, agglomeration and deactivation, and formation of carbon deposit. The scheme includes: stirring deionized water, sodium metaaluminate NaAlO2 and a dual template agent to obtain a clarified solution, adding fumed silica and performing stirring,then transferring the mixture into a polytetrafluoroethylene container, and conducting constant temperature heating and static crystallization in a reaction kettle, then performing cooling, and carrying out high temperature calcination, then taking nickel carbonate tetrahydrate, ammonium chloride and ammonia water, and performing stirring in deionized water, adding the molecular sieve and performing stirring, conducting hydrothermal synthesis for certain period of time, then conducting washing and pumping filtration, retaining the solid product, and conducting drying. The prepared hierarchicalporous Beta molecular sieve is rich in micro-mesoporous biphasic highly interconnected pore structure. The prepared catalyst is core-shell-like structure catalyst, and has high yield.